Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …

Human mesenchymal stem cell (hMSC) derived extracellular vesicles (EVs) have shown
therapeutic potential in recent studies. However, the corresponding therapeutic components …

Granulation tissue formation constitutes a key step during wound healing of the skin and
other organs. Granulation tissue concomitantly initiates regenerative M2 macrophages …

Human mesenchymal stem cells (hMSCs) are a promising candidate in cell therapy as they
exhibit multilineage differentiation, homing to the site of injury, and secretion of trophic …

Introduction: One of the key factors that may influence the therapeutic potential of
mesenchymal stem/stromal cells (MSCs) is their metabolism. The switch between …

Preclinical studies have shown that mesenchymal stem cells have a positive effect in
perinatal brain injury models. The mechanisms that cause these neurotherapeutic effects …

Human mesenchymal stem cells (hMSCs) promote endogenous tissue regeneration and
have become a promising candidate for cell therapy. However, in vitro culture expansion of …

Mesenchymal stem cell (MSC) transplantation alleviates metabolic defects in diseased
recipient cells by intercellular mitochondrial transport (IMT). However, the effect of host …

Mesenchymal stromal cell (MSC) therapy has seen increased attention as a possible option
to treat a number of inflammatory conditions including COVID-19 acute respiratory distress …