Multiple organ failure (MOF) has reached epidemic proportions in most intensive care units
and is fast becoming the most common cause of death in the surgical intensive care unit …

Sepsis is frequently characterized by a number of metabolic abnormalities: increased
plasma lactate concentration, metabolic acidosis, increased glycolysis, and an abnormal" …

Study objective: To compare the ability of dopamine and norepinephrine to reverse
hemodynamic and metabolic abnormalities of human hyperdynamic septic shock. Design …

A prospective study was conducted on 34 stable septic patients to determine whether mild
hyperlactatemia is a marker of lactate overproduction or an indicator of lactate …

We hypothesized that inadequate oxygenation of peripheral tissues may be unrecognized in
critically ill patients and may worsen their prognosis. To test this hypothesis, we measured …

Initial therapy of shock in the emergency department (ED) emphasizes the normalization of
physiologic variables such as heart rate (HR), mean arterial pressure (MAP), and central …

Diminished availability of oxygen at the cellular level might account for organ dysfunction in
sepsis. Although the classical forms of tissue hypoxia due to hypoxemia, anemia, or …

Plasma immunoreactive endothelin-1 concentrations were determined by
radioimmunoassay in 11 septic patients during the first 24 hours after the development of the …

Now completely up to date to meet the needs of today's pediatric nurses, Mary Fran
Hazinski's Nursing Care of the Critically Ill Child, 3rd Edition, remains the foundational text of …

We asked whether the relationship between oxygen delivery and oxygen consumption is
different between patients who have sepsis and normal (n= 6) or increased (n= 8) …