Tumor cell invasion in glioblastoma

A Vollmann-Zwerenz, V Leidgens, G Feliciello… - International journal of …, 2020 - mdpi.com
Glioblastoma (GBM) is a particularly devastating tumor with a median survival of about 16
months. Recent research has revealed novel insights into the outstanding heterogeneity of …

Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

[HTML][HTML] In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

T Stanković, T Ranđelović, M Dragoj, SS Burić… - Drug Resistance …, 2021 - Elsevier
The poor response of glioblastoma to current treatment protocols is a consequence of its
intrinsic drug resistance. Resistance to chemotherapy is primarily associated with …

The ubiquitin hydrolase OTUB1 promotes glioma cell stemness via suppressing ferroptosis through stabilizing SLC7A11 protein

X Zhao, M Zhou, Y Yang, M Luo - Bioengineered, 2021 - Taylor & Francis
The ubiquitin hydrolase OTUB1 has been elucidated to be highly expressed in tumors,
however, its roles in glioma progression are still confusing. Here, via analyzing several …

Lessons learned in using laser interstitial thermal therapy for treatment of brain tumors: a case series of 238 patients from a single institution

J Shao, NR Radakovich, M Grabowski… - World Neurosurgery, 2020 - Elsevier
Background Laser interstitial thermal therapy (LITT) is a novel, minimally invasive alternative
to craniotomy, and as with any new technology, comes with a learning curve. Objective We …

The efficacy of a coordinated pharmacological blockade in glioblastoma stem cells with nine repurposed drugs using the CUSP9 strategy

E Skaga, IØ Skaga, Z Grieg, CJ Sandberg… - Journal of cancer …, 2019 - Springer
Purpose Constructed from a theoretical framework, the coordinated undermining of survival
paths in glioblastoma (GBM) is a combination of nine drugs approved for non-oncological …

Barriers to overcoming immunotherapy resistance in glioblastoma

JS Gillette, EJ Wang, RS Dowd, SA Toms - Frontiers in Medicine, 2023 - frontiersin.org
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor, known
for its poor prognosis and high recurrence rate. Current standard of care includes surgical …

Neuroblastoma invasion strategies are regulated by the extracellular matrix

C Gavin, N Geerts, B Cavanagh, M Haynes… - Cancers, 2021 - mdpi.com
Simple Summary Paediatric cancer research in general and neuroblastoma, in particular,
has minimal preclinical models of metastasis. As 50% of primary neuroblastomas have …

Glycomaterials to investigate the functional role of aberrant glycosylation in Glioblastoma

C Tondepu, L Karumbaiah - Advanced healthcare materials, 2022 - Wiley Online Library
Glioblastoma (GBM) is a stage IV astrocytoma that carries a dismal survival rate of≈ 10
months postdiagnosis and treatment. The highly invasive capacity of GBM and its ability to …

FABP5 enhances malignancies of lower‐grade gliomas via canonical activation of NF‐κB signaling

Y Wang, A Wahafu, W Wu, J Xiang… - Journal of cellular …, 2021 - Wiley Online Library
Low‐grade gliomas (LGGs) are grade III gliomas based on the WHO classification with
significant genetic heterogeneity and clinical properties. Traditional histological …