Cardiovascular diseases (CVDs) cause significant mortality globally. Notably, CVDs
disproportionately negatively impact underserved populations, such as those that are …

Plasma and serum are widely used for proteomics-based biomarker discovery. However,
analysis of these biofluids is highly challenging due to the complexity and wide dynamic …

Heart failure (HF) is a complex disease in which cardiomyocyte injury leads to a cascade of
inflammatory and fibrosis pathway activation, thereby causing decrease in cardiac function …

The medico-legal term “sudden death (SD)” refers to those deaths that are not preceded by
significant symptoms. SD in apparently healthy individuals (newborn through to adults) …

Sudden cardiac death (SCD) caused by acute ischemic heart disease (IHD) is a major
cause of sudden death worldwide. Circular RNAs (circRNAs) are abundant in the heart and …

Cathepsin C (CTSC) is a lysosomal cysteine protease constitutively expressed at high levels
in the lung, kidney, liver, and spleen. It plays a key role in the activation of serine proteases …

This study was aimed at identifying molecular markers associated with the pathogenesis of
sudden cardiac death (SCD). It provides a proteomic analysis of human left anterior …

Objective C-reactive protein (CRP) is a powerful predictor of and risk factor for
cardiovascular disease. However, the relationship between CRP and sudden death (SD) is …

Sudden cardiac death results from arrhythmias commonly caused by channelopathies and
cardiomyopathies, often due to several genetic factors. An emerging concept is that these …

Objective The aim of this study is to identify a rapid, sensitive, and non-destructive auxiliary
approach for postmortem diagnosis of SCD, addressing the challenges faced in forensic …