Crosstalk between cholesterol metabolism and psoriatic inflammation

L Luo, Y Guo, L Chen, J Zhu, C Li - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic autoinflammatory skin disease associated with multiple comorbidities,
with a prevalence ranging from 2 to 3% in the general population. Decades of preclinical …

Therapeutic targets for endothelial dysfunction in vascular diseases

DTN Huynh, KS Heo - Archives of Pharmacal Research, 2019 - Springer
Vascular endothelial cells are located on the surface of the blood vessels. It has been
recognized as an important barrier to the regulation of vascular homeostasis by regulating …

Baccharis dracunculifolia (Asteraceae) essential oil displays anti-inflammatory activity in models of skin inflammation

MM Brandenburg, FG Rocha, PL Pawloski… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Baccharis dracunculifolia (Asteraceae) is a
commonly used plant in traditional medicine known as “alecrim-do-campo”. Popularly it has …

Topical application of simvastatin acid sodium salt and atorvastatin calcium salt in vitiligo patients. Results of the randomized, double-blind EVRAAS pilot study

A Niezgoda, A Winnicki, J Krysiński, P Niezgoda… - Scientific Reports, 2024 - nature.com
Contemporary treatment of vitiligo remains a great challenge to practitioners. The vast
majority of currently conducted clinical trials of modern therapeutic methods are focused on …

Pelargonidin reduces the TPA induced transformation of mouse epidermal cells–potential involvement of Nrf2 promoter demethylation

S Li, W Li, C Wang, R Wu, R Yin, HC Kuo… - Chemico-biological …, 2019 - Elsevier
Pelargonidin, a well-known natural anthocyanidin found in berries strawberries, blueberries,
red radishes and other natural foods, has been found to possess health beneficial effects …

Topical atorvastatin 1% for prevention of skin toxicity in patients receiving radiation therapy for breast cancer: a randomized, double-blind, placebo-controlled trial

A Ghasemi, Z Ghashghai, J Akbari… - European journal of …, 2019 - Springer
Background and purpose The purpose of this randomized, placebo-controlled, double-blind
study was to investigate the preventive effect of topical administration of atorvastatin (ATV) …

Three Constituents of Moringa oleifera Seeds Regulate Expression of Th17-Relevant Cytokines and Ameliorate TPA-Induced Psoriasis-Like Skin Lesions in Mice

N Ma, Q Tang, WT Wu, XA Huang, Q Xu, GL Rong… - Molecules, 2018 - mdpi.com
As a folk medicine, Moringa oleifera L. is used effectively to treat inflammatory conditions
and skin diseases. However, its mechanism of action is not well understood, limiting its …

[HTML][HTML] Tat-ATOX1 inhibits inflammatory responses via regulation of MAPK and NF-κB pathways

DW Kim, MJ Shin, YJ Choi, HJ Kwon, SH Lee, S Lee… - BMB …, 2018 - ncbi.nlm.nih.gov
Abstract Antioxidant 1 (ATOX1) protein has been reported to exhibit various protective
functions, including antioxidant and chaperone. However, the effects of ATOX1 on the …

Transcriptomic analysis of the mechanisms for alleviating psoriatic dermatitis using taodan granules in an imiquimod-induced psoriasis-like mouse model

L Kuai, Y Luo, K Qu, Y Ru, Y Luo, X Ding… - Frontiers in …, 2021 - frontiersin.org
Taodan granules (TDGs) are clinically efficacious for treating psoriasis, buttheir specific
mechanisms of action are unclear. In this study, we determined the concentrations of …

Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic …

M Madsen, PR Hansen, LB Nielsen, K Hartvigsen… - BMC dermatology, 2016 - Springer
Background Risk of cardiovascular disease is increased in patients with psoriasis, but
molecular mechanisms linking the two conditions have not been clearly established. Lack of …