Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications
OG Salnikov, DB Burueva, IV Skovpin… - Mendeleev …, 2023 - Elsevier
Signal amplification by reversible exchange (SABRE) is a rapidly developing nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …
Rapid 13C Hyperpolarization of the TCA Cycle Intermediate α-Ketoglutarate via SABRE-SHEATH
α-Ketoglutarate is a key biomolecule involved in a number of metabolic pathways─ most
notably the TCA cycle. Abnormal α-ketoglutarate metabolism has also been linked with …
notably the TCA cycle. Abnormal α-ketoglutarate metabolism has also been linked with …
Advancing homogeneous catalysis for parahydrogen-derived hyperpolarisation and its NMR applications
BJ Tickner, VV Zhivonitko - Chemical Science, 2022 - pubs.rsc.org
Parahydrogen-induced polarisation (PHIP) is a nuclear spin hyperpolarisation technique
employed to enhance NMR signals for a wide range of molecules. This is achieved by …
employed to enhance NMR signals for a wide range of molecules. This is achieved by …
Efficient SABRE-SHEATH Hyperpolarization of Potent Branched-Chain-Amino-Acid Metabolic Probe [1-13C]ketoisocaproate
Efficient 13C hyperpolarization of ketoisocaproate is demonstrated in natural isotopic
abundance and [1-13C] enriched forms via SABRE-SHEATH (Signal Amplification By …
abundance and [1-13C] enriched forms via SABRE-SHEATH (Signal Amplification By …
Interplay of Near-Zero-Field Dephasing, Rephasing, and Relaxation Dynamics and [1-13C]Pyruvate Polarization Transfer Efficiency in Pulsed SABRE-SHEATH
Hyperpolarized [1-13C] pyruvate is a revolutionary molecular probe enabling ultrafast
metabolic MRI scans in 1 min. This technology is now under evaluation in over 30 clinical …
metabolic MRI scans in 1 min. This technology is now under evaluation in over 30 clinical …
Ultrafast Laplace NMR to study metal–ligand interactions in reversible polarisation transfer from parahydrogen
Laplace Nuclear Magnetic Resonance (NMR) can determine relaxation parameters and
diffusion constants, giving valuable information about molecular structure and dynamics …
diffusion constants, giving valuable information about molecular structure and dynamics …
Toward Optimizing and Understanding Reversible Hyperpolarization of Lactate Esters Relayed from para-Hydrogen
BJ Tickner, SKM Svensson, J Vaara… - The Journal of Physical …, 2022 - ACS Publications
The SABRE-Relay hyperpolarization method is used to enhance the 1H and 13C NMR
signals of lactate esters, which find use in a wide range of medical, pharmaceutical, and …
signals of lactate esters, which find use in a wide range of medical, pharmaceutical, and …
Metal-Mediated Catalytic Polarization Transfer from para Hydrogen to 3,5-Dihalogenated Pyridines
BJ Tickner, M Dennington, BG Collins, CA Gater… - ACS …, 2024 - ACS Publications
The neutral catalysts [IrCl (H) 2 (NHC)(substrate) 2] or [IrCl (H) 2 (NHC)(substrate)(sulfoxide)
] are used to transfer polarization from para hydrogen (p H2) to 3, 5-dichloropyridine and 3, 5 …
] are used to transfer polarization from para hydrogen (p H2) to 3, 5-dichloropyridine and 3, 5 …
SABRE-SHEATH Hyperpolarization of [1,5-13C2]Z-OMPD for Noninvasive pH Sensing
Hyperpolarized (HP) 13C-labeled probes are emerging as promising agents to
noninvasively image pH in vivo. HP [1, 5-13C2] Z-OMPD (Z-4-methyl-2-oxopent-3-enedioic …
noninvasively image pH in vivo. HP [1, 5-13C2] Z-OMPD (Z-4-methyl-2-oxopent-3-enedioic …
Theory and computation of nuclear shielding
T Kupka - 2020 - books.rsc.org
A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …