Microfluidic Platforms for Real‐Time In Situ Monitoring of Biomarkers for Cellular Processes

C Lou, H Yang, Y Hou, H Huang, J Qiu… - Advanced …, 2024 - Wiley Online Library
Cellular processes are mechanisms carried out at the cellular level that are aimed at
guaranteeing the stability of the organism they comprise. The investigation of cellular …

Integration of immune cells in organs-on-chips: a tutorial

L Van Os, B Engelhardt, OT Guenat - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Viral and bacterial infections continue to pose significant challenges for numerous
individuals globally. To develop novel therapies to combat infections, more insight into the …

Quantification of cell migration: metrics selection to model application

Y Hu, ML Becker, RK Willits - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Cell migration plays an essential role in physiological and pathological states, such as
immune response, tissue generation and tumor development. This phenomenon can occur …

[HTML][HTML] Immune cell extravasation in an organ-on-chip to model lung inflammation

L van Os, J Yeoh, G Witz, D Ferrari, P Krebs… - European Journal of …, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) is a severe lung condition with high mortality
and various causes, including lung infection. No specific treatment is currently available and …

Salmonella manipulates macrophage migration via SteC-mediated myosin light chain activation to penetrate the gut-vascular barrier

Y Dai, M Zhang, X Liu, T Sun, W Qi, W Ding… - The EMBO …, 2024 - embopress.org
The intestinal pathogen Salmonella enterica rapidly enters the bloodstream after the
invasion of intestinal epithelial cells, but how Salmonella breaks through the gut-vascular …

Biofabrication Directions in Recapitulating the Immune System‐on‐a‐Chip

R Janssen, L Benito‐Zarza, P Cleijpool… - Advanced …, 2024 - Wiley Online Library
Ever since the implementation of microfluidics in the biomedical field, in vitro models have
experienced unprecedented progress that has led to a new generation of highly complex …

Utilizing Laser Direct Writing to Fabricate In Vitro Bioengineered Systems for Elucidating Cellular Dynamics in Breast Tumor and Wound Microenvironments

J Saksena - 2023 - search.proquest.com
Laser direct writing is a powerful technique to additively and subtractively process biological
materials for fabricating in vitro bioengineered constructs. Additive laser direct write …

Laser Direct Write Bioprinting Enriched Cell Types in the Breast Tumor Microenvironment

J Saksena, ME Burow, DB Chrisey - Authorea Preprints, 2023 - techrxiv.org
The most enriched cell types in the breast tumor microenvironment are cancer cells, cancer-
associated fibroblasts, and tumor-associated macrophages. To recapitulate the cellular …

DUSP2 Deletion Inhibits Macrophage Migration by Inhibiting ERK Activation in Zebrafish

YJ Li, XL Wang, LY Shi, ZY Wang, ZA Zhao, SC Ge… - Fishes, 2023 - mdpi.com
Dual-specificity phosphatase 2 (DUSP2) regulates the activation of members of the mitogen-
activated protein kinase (MAPK) family, which is involved in a variety of cellular processes …