The cell-free system: A new apparatus for affordable, sensitive, and portable healthcare

CE Copeland, A Langlois, J Kim, YC Kwon - Biochemical Engineering …, 2021 - Elsevier
The cell-free system is a tool that harnesses the complex biological processes outside of
living cells. Owing to the system's superior flexibility and manipulability, it has matured its …

Gene circuit performance characterization and resource usage in a cell-free “breadboard”

D Siegal-Gaskins, ZA Tuza, J Kim… - ACS synthetic …, 2014 - ACS Publications
The many successes of synthetic biology have come in a manner largely different from those
in other engineering disciplines; in particular, without well-characterized and simplified …

A cell‐free expression and purification process for rapid production of protein biologics

CJ Sullivan, ED Pendleton, HH Sasmor… - Biotechnology …, 2016 - Wiley Online Library
Cell‐free protein synthesis has emerged as a powerful technology for rapid and efficient
protein production. Cell‐free methods are also amenable to automation and such systems …

Continuous protein production in nanoporous, picolitre volume containers

P Siuti, ST Retterer, MJ Doktycz - Lab on a Chip, 2011 - pubs.rsc.org
The synthetic manufacture of functional proteins enables a bottom-up understanding of the
workings of biological systems and opens new opportunities for the treatment of disease …

Cell-Free Synthetic Biology: The Novel Approach Towards the Biotechnological Applications

H Qaiser, M Uzair, A Arshad, JZK Khattak… - … of Synthetic Biology in …, 2023 - igi-global.com
Innovations in sustainable biomanufacturing are made possible by cell-free synthetic
biology advances. Cell-free workflows frequently combine purified enzymes with cell …

Portable fluidic platform for rapid cell-free production of protein biologics

J Dresios, RH Griffey, CJ Sullivan… - US Patent …, 2018 - Google Patents
A portable fluidic platform for rapid and flexible end-to-end production of recombinant
protein biologics includes a bioreactor system hosting stable and robust cell-free translation …

Design of a Regulated Micromachined Air-Sniffer Using Thermal Transpiration Effect for e-Nose Applications

MA Raju - 2021 - scholar.uwindsor.ca
Microfluidics artificial olfaction systems are used for plant disease diagnosis in the
agricultural field. In an electronic nose, the sniffer draws the air towards an array of gas …

Resource usage and gene circuit performance characterization in a cell-free 'breadboard'

D Siegal-Gaskins, ZA Tuza, J Kim, V Noireaux… - bioRxiv, 2013 - biorxiv.org
The many successes of synthetic biology have come in a manner largely different from those
in other engineering disciplines; in particular, without well-characterized and simplified …

Nano-enabled synthetic biology: A cell mimic based sensing platform for exploiting biochemical networks

P Siuti - 2011 - trace.tennessee.edu
Exploring and understanding how the smallest scale features of a cell affect biochemical
reactions has always been a challenge. Nanoscale fabrication advancements have allowed …

Portable fluidic platform for rapid cell-free production of protein biologics

J Dresios, RH Griffey, CJ Sullivan… - US Patent …, 2023 - Google Patents
2020-04-10 Assigned to LEIDOS, INC. reassignment LEIDOS, INC. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HICKS, WILLIAM L …