B cells in multiple sclerosis—from targeted depletion to immune reconstitution therapies

MT Cencioni, M Mattoscio, R Magliozzi… - Nature Reviews …, 2021 - nature.com
Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of …

Use of convalescent plasma in COVID‐19 patients with immunosuppression

JW Senefeld, SA Klassen, SK Ford, KA Senese… - …, 2021 - Wiley Online Library
In the absence of effective countermeasures, human convalescent plasma has been widely
used to treat severe acute respiratory syndrome coronavirus 2, the causative agent of novel …

Convalescent plasma therapy for B-cell–depleted patients with protracted COVID-19

T Hueso, C Pouderoux, H Péré… - Blood, The Journal …, 2020 - ashpublications.org
Anti-CD20 monoclonal antibodies are widely used for the treatment of hematological
malignancies or autoimmune disease but may be responsible for a secondary humoral …

[PDF][PDF] Unveiling B Cell Mediated Immunity in HIV Infection: Insights, Challenges, and Potential Therapeutic Avenues

EI Obeagu, AF Anyiam, GU Obeagu - Elite Journal of HIV, 2024 - researchgate.net
Abstract Human Immunodeficiency Virus (HIV) poses a significant global health challenge,
necessitating a deeper comprehension of the immune responses engaged in infection. B …

Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-α-mediated ERK1/2 and JAK …

Y Qin, ML Cai, HZ Jin, W Huang, C Zhu… - Annals of the …, 2022 - ard.bmj.com
Objectives Age-associated B cells (ABCs) are a recently identified B cell subset, whose
expansion has been increasingly linked to the pathogenesis of autoimmune disorders. This …

[HTML][HTML] Inhibition of Bruton's tyrosine kinase interferes with pathogenic B-cell development in inflammatory CNS demyelinating disease

S Torke, R Pretzsch, D Häusler, P Haselmayer… - Acta …, 2020 - Springer
Abstract Anti-CD20-mediated B-cell depletion effectively reduces acute multiple sclerosis
(MS) flares. Recent data shows that antibody-mediated extinction of B cells as a lasting …

Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches

A Merino‐Vico, G Frazzei… - European journal of …, 2023 - Wiley Online Library
Autoimmune diseases are characterized by the recognition of self‐antigens by the immune
system, which leads to inflammation and tissue damage. B cells are directly and indirectly …

Early intestinal microbial features are associated with CD4 T-cell recovery after allogeneic hematopoietic transplant

O Miltiadous, NR Waters, H Andrlová… - Blood, The Journal …, 2022 - ashpublications.org
Low intestinal microbial diversity is associated with poor outcomes after allogeneic
hematopoietic cell transplantation (HCT). Using 16S rRNA sequencing of 2067 stool …

Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis

F Schweitzer, S Laurent, GR Fink… - Current opinion in …, 2019 - journals.lww.com
Age and the risks of high-efficacy disease modifying drugs i... : Current Opinion in
Neurology Age and the risks of high-efficacy disease modifying drugs in multiple sclerosis …

[HTML][HTML] Immune mechanisms in epileptogenesis: update on diagnosis and treatment of autoimmune epilepsy syndromes

J Flammer, T Neziraj, S Rüegg, AK Pröbstel - Drugs, 2023 - Springer
Seizures and epilepsy can result from various aetiologies, yet the underlying cause of
several epileptic syndromes remains unclear. In that regard, autoimmune-mediated …