Conventional and state-of-the-art detection methods of bovine spongiform encephalopathy (BSE)

M Olech - International Journal of Molecular Sciences, 2023 - mdpi.com
Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disease that belongs
to a group of diseases known as transmissible spongiform encephalopathies (TSEs). It is …

Proteinase K and the structure of PrPSc: The good, the bad and the ugly

CJ Silva, E Vázquez-Fernández, B Onisko… - Virus research, 2015 - Elsevier
Infectious proteins (prions) are, ironically, defined by their resistance to proteolytic digestion.
A defining characteristic of the transmissible isoform of the prion protein (PrP Sc) is its partial …

Detection and discrimination of classical and atypical L-type bovine spongiform encephalopathy by real-time quaking-induced conversion

CD Orrú, A Favole, C Corona, M Mazza… - Journal of clinical …, 2015 - Am Soc Microbiol
Statutory surveillance of bovine spongiform encephalopathy (BSE) indicates that cattle are
susceptible to both classical BSE (C-BSE) and atypical forms of BSE. Atypical forms of BSE …

Detection of atypical H-type bovine spongiform encephalopathy and discrimination of bovine prion strains by real-time quaking-induced conversion

K Masujin, CD Orrú, K Miyazawa… - Journal of clinical …, 2016 - Am Soc Microbiol
Prion diseases of cattle include the classical bovine spongiform encephalopathy (C-BSE)
and the atypical H-type BSE (H-BSE) and L-type BSE (L-BSE) strains. Although the C-and L …

[HTML][HTML] Atypical BSE: current knowledge and knowledge gaps

S Dudas, S Czub - Food Safety, 2017 - jstage.jst.go.jp
Atypical BSE is an invariably fatal neurologic disease of cattle caused by misfolded prion
proteins with different conformations than those associated with classical BSE. Evidence …

Biochemical Characteristics and PrPSc Distribution Pattern in the Brains of Cattle Experimentally Challenged with H-type and L-type Atypical BSE

G Priemer, A Balkema-Buschmann, B Hills… - PloS one, 2013 - journals.plos.org
Besides the classical form of bovine spongiform encephalopathy (BSE) that has been known
for almost three decades, two atypical forms designated H-type and L-type BSE have …

Protocol for further laboratory investigations into the distribution of infectivity of Atypical BSE

European Food Safety Authority - EFSA Journal, 2014 - Wiley Online Library
Abstract Information on the pathogenesis and tissue distribution of Atypical Bovine
Spongiform Encephalopathy (BSE) in cattle through the study of field cases and …

Encefalopatia espongiforme bovina atípica: uma revisão

EE Laurindo, IR Barros Filho - Arquivos do Instituto Biológico, 2017 - SciELO Brasil
A encefalopatia espongiforme bovina (EEB), causada por um príon infectante, surgiu na
década de 1980 na Europa como uma nova doença nos rebanhos bovinos e, desde então …

Phenotypical variability in bovine spongiform encephalopathy: Epidemiology, pathogenesis, and diagnosis of classical and atypical forms

C Corona, EV Costassa, B Iulini, M Caramelli… - Progress in molecular …, 2017 - Elsevier
After thirty years, bovine spongiform encephalopathy (BSE) still represents the biggest crisis
in the field of food safety. Initially detected in the United Kingdom in 1986, BSE spread to …

Clinical, pathological, and molecular features of classical and L-type atypical-BSE in goats

E Vallino Costassa, A D'Angelo, M Mazza, D Meloni… - Plos one, 2018 - journals.plos.org
Monitoring of small ruminants for transmissible spongiform encephalopathies (TSEs) has
recently become more relevant after two natural scrapie suspected cases of goats were …