Application of animal models in cancer research: recent progress and future prospects
Z Li, W Zheng, H Wang, Y Cheng, Y Fang… - Cancer management …, 2021 - Taylor & Francis
Animal models refers to the animal experimental objects and related materials that can
simulate human body established in medical research. As the second-largest disease in …
simulate human body established in medical research. As the second-largest disease in …
Dairy-based probiotic-fermented functional foods: An update on their health-promoting properties
Numerous studies have shown a link between the consumption of fermented dairy foods
and improved health outcomes. Since the early 2000s, especially probiotic-based fermented …
and improved health outcomes. Since the early 2000s, especially probiotic-based fermented …
Immunotherapy of glioblastoma: current strategies and challenges in tumor model development
Glioblastoma is the most common brain malignant tumor in the adult population, and
immunotherapy is playing an increasingly central role in the treatment of many cancers …
immunotherapy is playing an increasingly central role in the treatment of many cancers …
Natural killer cells: diverse functions in tumor immunity and defects in pre-neoplastic and neoplastic stages of tumorigenesis
Natural killer (NK) cells are the key immune effectors with the ability to mediate selection and
differentiation of a number of different cancer stem cells/undifferentiated tumors via lysis, and …
differentiation of a number of different cancer stem cells/undifferentiated tumors via lysis, and …
Progress in building clinically relevant patient‐derived tumor xenograft models for cancer research
W Wang, Y Li, K Lin, X Wang, Y Tu… - Animal Models and …, 2023 - Wiley Online Library
Patient‐derived tumor xenograft (PDX) models, a method involving the surgical extraction of
tumor tissues from cancer patients and subsequent transplantation into immunodeficient …
tumor tissues from cancer patients and subsequent transplantation into immunodeficient …
Infiltrating natural killer cells bind, lyse and increase chemotherapy efficacy in glioblastoma stem-like tumorospheres
Glioblastomas remain the most lethal primary brain tumors. Natural killer (NK) cell-based
therapy is a promising immunotherapeutic strategy in the treatment of glioblastomas, since …
therapy is a promising immunotherapeutic strategy in the treatment of glioblastomas, since …
Gut dysbiosis in pancreatic diseases: A causative factor and a novel therapeutic target
T Zhang, G Gao, HA Sakandar, LY Kwok, Z Sun - Frontiers in Nutrition, 2022 - frontiersin.org
Pancreatic-related disorders such as pancreatitis, pancreatic cancer, and type 1 diabetes
mellitus (T1DM) impose a substantial challenge to human health and wellbeing. Even …
mellitus (T1DM) impose a substantial challenge to human health and wellbeing. Even …
Characterizing hepatocellular carcinoma stem markers and their corresponding susceptibility to NK-cell based immunotherapy
Introduction Hepatocellular carcinoma (HCC) is the most common primary liver cancer and
is the fourth-leading cause of all cancer-related deaths around the world. Liver …
is the fourth-leading cause of all cancer-related deaths around the world. Liver …
ADCC against MICA/B is mediated against differentiated oral and pancreatic and not stem-like/poorly differentiated tumors by the NK cells; loss in cancer patients due …
Simple Summary Natural Killer cells are known to eliminate tumors directly or via antibody
dependent cellular cytotoxicity. The complete modes and mechanisms of such killings are …
dependent cellular cytotoxicity. The complete modes and mechanisms of such killings are …
Osteoclast-expanded super-charged NK-cells preferentially select and expand CD8+ T cells
Osteoclasts (OCs) and much less dendritic cells (DCs) induce significant expansion and
functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially …
functional activation of NK cells, and furthermore, the OC-expanded NK cells preferentially …