Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Disorders characterized by ischemia/reperfusion (I/R), such as myocardial infarction, stroke,
and peripheral vascular disease, continue to be among the most frequent causes of …

Rationale: Mitochondria are semiautonomous cellular organelles with their own genome,
which not only supply energy but also participate in cell death pathways. MicroRNAs …

Circulating microRNAs (c-microRNAs, c-miRNAs), which are present in almost all biological
fluids, are promising sensitive biomarkers for various diseases (oncological and …

In contrast to the wealth of proven therapies for heart failure with reduced ejection fraction
(HFrEF), therapeutic efforts in the past have failed to improve outcomes in heart failure with …

The leading cause of death in developed countries is cardiovascular disease, where
coronary heart disease is the main cause of death. Myocardial reperfusion is the most …

Significance: An inflammatory response follows an injury of any nature, and while such a
response is an attempt to promote healing, it may, itself, result in further injury. Recent …

Non-coding RNAs (ncRNAs) encompass a family of ubiquitous RNA molecules that lack
protein-coding potential and have tissue-specific expression. A significant body of evidence …

Coronary artery disease remains the leading cause of death. Acute myocardial infarction
(MI) is characterized by decreased blood flow to the coronary arteries, resulting in …

Recent studies have revealed the critical role of microRNAs (miRNAs) in regulating cardiac
injury. Among them, the cardiac enriched microRNA-1 (miR-1) has been extensively …