As an essential component of the maternal-fetal interface, the placental syncytiotrophoblast
layer contributes to a successful pregnancy by secreting hormones necessary for …

The use of in vitro tools to study trophoblast differentiation and function is essential to
improve understanding of normal and abnormal placental development. The relative …

The purpose of this review is to explore self-organizing mechanisms that pattern
microtubules (MTs) and spatially organize animal cell cytoplasm, inspired by recent …

Unique immunologic adaptations exist to successfully establish and maintain pregnancy
and to avoid an immune attack against the semi allogenic fetus. These adaptations occur …

Placentation in humans is precocious and highly invasive compared to other mammals.
Implantation is interstitial, with the conceptus becoming completely embedded within the …

Complete hydatidiform mole (HM) is a gestational trophoblastic disease resulting in
hyperproliferation of trophoblast cells and absence of embryo development. Mutations in the …

Placental barrier regulates maternal-fetal interchange protecting the baby from damage
caused by substances found in the uterine environment or circulating in the vascular system …

Nuclear movement is crucial for the development of many cell types and organisms. Nuclear
movement is highly conserved, indicating its necessity for cellular function and development …

Cells in many tissues, such as bone, muscle, and placenta, fuse into syncytia to acquire new
functions and transcriptional programs. While it is known that fused cells are specialized, it is …

Maternal depressive symptoms during pregnancy predict increased psychiatric problems in
children. The underlying biological mechanisms remain unclear. Hence, we examined …