Recent studies of inherited disorders of phosphate metabolism have shed new light on the
understanding of phosphate metabolism. Phosphate has important functions in the body and …

Proximal renal tubular acidosis (RTA)(Type II RTA) is characterized by a defect in the ability
to reabsorb HCO3 in the proximal tubule. This is usually manifested as bicarbonate wastage …

Purpose The European Intergroup Cooperative Ewing's Sarcoma Study investigated
whether cyclophosphamide has a similar efficacy as ifosfamide in standard-risk (SR) …

Background Improvements in diagnostics and treatment for paediatric malignancies resulted
in a major increase in survival. However, childhood cancer survivors (CCS) are at risk of …

Many different drugs and agents may cause nephrotoxic acute kidney injury (AKI) in
children. Predisposing factors such as age, pharmacogenetics, underlying disease, the …

Abstract Hypophosphatemia (serum phosphorus concentration< 2.5 mg/dl, 0.8 mmol/l),
although rare in the general population, is commonly observed in hospitalized patients and …

Soft tissue sarcoma (STS) is a biologically heterogeneous malignancy with over 50
subtypes. Historically, there have been few systemic treatment options for this relatively rare …

Purpose To improve risk-adapted therapy for localized childhood soft tissue sarcoma within
an international multicenter setting. Patients and Methods Four hundred forty-one patients …

Improvements in childhood cancer therapy have led to increasing numbers of long‐term
survivors. These survivors are at risk for a variety of late effects due to the disease itself …

Purpose Ifosfamide is widely used in pediatric oncology but its nephrotoxicity may become a
significant issue in survivors. This study is aimed at evaluating the incidence of late renal …