* The AVMA Panel on Euthanasia develops the content of the guidelines, with support from
its working groups. The panel is required to do a comprehensive review and update of the …

Euthanasia is one of the most commonly performed procedures in biomedical research,
involving tens of millions of animals in North America and Europe every year. The use of …

The optimal choice of euthanasia method for laboratory rodents depends on a number of
factors, including the scientific goals of the study, the need to minimize animal pain and/or …

Abstract Background The Canadian Council on Animal Care and American Veterinary
Medical Association classify intraperitoneal (IP) pentobarbital as an acceptable euthanasia …

Background Alzheimer's disease (AD), one of the major causes of dementia, is an
overwhelming neurodegenerative disease that particularly affects the brain, leading to …

Adolescence is a brain maturation developmental period during which remodeling and
changes in synaptic plasticity and neural connectivity take place in some brain regions …

Sodium pentobarbital and pentobarbital combination products are commonly used by
veterinarians throughout the US for euthanasia of their animal patients. The AVMA …

We redefined Robert's prototypical cytoprotection model, namely the intragastric
administration of 96% alcohol in order to generate a general peripheral and central …

Abstract Background Extracellular vesicles (EVs) are heterogeneous membrane vesicles
secreted by cells in extracellular spaces that play an important role in intercellular …

An effective and pain-free killing method is required to achieve the goal of euthanasia, a
“good death”. Overdose of sodium pentobarbital (PB) by intraperitoneal (IP) injection is a …