Background AS1411 is a 26-mer G-rich DNA oligonucleotide that forms a variety of G-
quadruplex structures. It was identified based on its cancer-selective antiproliferative activity …

Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

Nucleolin (NCL) is a multifunctional protein that mainly localized in the nucleolus, it is also
found in the nucleoplasm, cytoplasm and cell membrane. The three main structural domains …

Targeted delivery of therapeutic nanoparticles in a disease-specific manner represents a
potentially powerful technology especially when treating infiltrative brain tumors such as …

BACKGROUND: Lactoferrin (Lf) is an 80kDa iron-binding glycoprotein of the transferrin
family. It is abundant in milk and in most biological fluids and is a cell-secreted molecule that …

Certain guanine-rich (G-rich) DNA and RNA molecules can associate intermolecularly or
intramolecularly to form four stranded or “quadruplex” structures, which have unusual …

Lactoferrin (LF) is an 80kDa iron-binding glycoprotein of the transferrin family that is
expressed in most biological fluids and is a major component of the mammalian innate …

Lactoferrin (Lf), a cationic glycoprotein able to chelate two ferric irons per molecule, is
synthesized by exocrine glands and neutrophils. Since the first anti-microbial function …

Lactoferrin (LF) is a member of the transferrin family that is expressed and secreted by
glandular epithelial cells and is found in the secondary granules of neutrophils. Originally …

Aptamers, also termed as decoys or “chemical antibodies,” represent an emerging class of
therapeutics. They are short DNA or RNA oligonucleotides or peptides that assume a …