Adverse drug reactions (ADR) remain the major problems in healthcare. Most severe ADR
are unpredictable, dose-independent and termed as type B idiosyncratic reactions. Recent …

Response to medications, the principal treatment modality for acute and chronic diseases, is
highly variable, with 40–70% of patients exhibiting lack of efficacy or adverse drug reactions …

Background Co-trimoxazole, a sulfonamide antibiotic, is used to treat a variety of infections
worldwide, and it remains a common first-line medicine for prophylaxis against …

Introduction: Beta-lactam antibiotics are one of the most common causes of antibiotics-
related severe cutaneous adverse reactions (SCARs) including Stevens–Johnson syndrome …

Severe cutaneous adverse reactions (SCARs), which include Stevens–Johnson syndrome
and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also …

Background Evidence is lacking on the association between antibiotic use and risk of
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Asians. Objective …

Introduction: The clinical manifestations of cutaneous adverse drug reactions are variable
with different severity. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis …

Background Because severe cutaneous adverse reactions (SCARs), such as Stevens-
Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with …

Background: The Stevens-Johnson syndrome (SJS) is a severe skin reaction to non-
steroidal anti-inflammatory drugs (NSAIDs), and can even be life-threatening. However …

Immune checkpoint inhibitors (ICI) represent new anticancer agents and have been used
worldwide. However, ICI can potentially induce life-threatening severe cutaneous adverse …