Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency

Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …

Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance

M Xu, Y Qi, G Liu, Y Song, X Jiang, B Du - ACS nano, 2023 - ACS Publications
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Recent advances in tumor targeting via EPR effect for cancer treatment

MA Subhan, SSK Yalamarty, N Filipczak… - Journal of personalized …, 2021 - mdpi.com
Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …

Controlled anti-cancer drug release through advanced nano-drug delivery systems: Static and dynamic targeting strategies

FM Kashkooli, M Soltani, M Souri - Journal of controlled release, 2020 - Elsevier
Advances in nanomedicine, including early cancer detection, targeted drug delivery, and
personalized approaches to cancer treatment are on the rise. For example, targeted drug …

Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines

VG Bandi, MP Luciano, M Saccomano, NL Patel… - Nature …, 2022 - nature.com
Recent progress has shown that using wavelengths between 1,000 and 2,000 nm, referred
to as the shortwave-infrared or near-infrared (NIR)-II range, can enable high-resolution in …

Supramolecular assembly confined purely organic room temperature phosphorescence and its biological imaging

WL Zhou, W Lin, Y Chen, Y Liu - Chemical Science, 2022 - pubs.rsc.org
Purely organic room temperature phosphorescence, especially in aqueous solution, is
attracting increasing attention owing to its large Stokes shift, long lifetime, low preparation …

Cancer nanomedicine: progress, challenges and opportunities

J Shi, PW Kantoff, R Wooster, OC Farokhzad - Nature reviews cancer, 2017 - nature.com
The intrinsic limits of conventional cancer therapies prompted the development and
application of various nanotechnologies for more effective and safer cancer treatment …

Transport of drugs from blood vessels to tumour tissue

MW Dewhirst, TW Secomb - Nature Reviews Cancer, 2017 - nature.com
The effectiveness of anticancer drugs in treating a solid tumour is dependent on delivery of
the drug to virtually all cancer cells in the tumour. The distribution of drug in tumour tissue …

Ligand-targeted drug delivery

M Srinivasarao, PS Low - Chemical reviews, 2017 - ACS Publications
Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …