Biological technologies are fundamentally unlike any other because biology evolves.
Bioengineering therefore requires novel design methodologies with evolution at their core …

Synthetic biology aims to engineer biological systems for customized tasks through the
bottom-up assembly of fundamental building blocks, which requires high-quality libraries of …

Introduction: Historically, drug development and marketing failures have been experienced
by pharma organizations largely from insufficient human-predictability of biological data …

Converging theoretical and empirical evidence points to suicide being a fundamentally
aleatory event—that risk of suicide is opaque to useful assessment at the level of the …

Gene expression control based on clustered regularly interspaced short palindromic repeats
(CRISPR) has emerged as a powerful approach for constructing synthetic gene circuits …

A promoter plays a crucial role in controlling the expression of the target gene in cells, thus
being one of the key biological parts for synthetic biology practices. Although significant …

Transgenic technology can transfer favorable traits regardless of reproductive isolation and
is an important method in plant synthetic biology and genetic improvement. Complex …

Synthetic microbial community has widely concerned in the fields of agriculture, food and
environment over the past few years. However, there is little consensus on the method to …

Engineering synthetic regulatory circuits with precise input-output behavior—a central goal
in synthetic biology—remains encumbered by the inherent molecular complexity of cells …

Antimicrobial resistance (AMR) is an emerging global health crisis that is undermining
advances in modern medicine and, if unmitigated, threatens to kill 10 million people per year …