Multiple sclerosis: mechanisms and immunotherapy

C Baecher-Allan, BJ Kaskow, HL Weiner - Neuron, 2018 - cell.com
Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …

Environmental and genetic risk factors for MS: an integrated review

E Waubant, R Lucas, E Mowry, J Graves… - Annals of clinical …, 2019 - Wiley Online Library
Recent findings have provided a molecular basis for the combined contributions of
multifaceted risk factors for the onset of multiple sclerosis (MS). MS appears to start as a …

The role of diet in multiple sclerosis: mechanistic connections and current evidence

I Katz Sand - Current nutrition reports, 2018 - Springer
Abstract Purpose of Review This review seeks to examine current research related to the
role of diet in multiple sclerosis (MS). Recent Findings Recent research in preclinical …

Multiple sclerosis risk factors and pathogenesis

B Nourbakhsh, EM Mowry - CONTINUUM: Lifelong Learning in …, 2019 - journals.lww.com
PURPOSE OF REVIEW This article summarizes recent advances in the identification of
genetic and environmental factors that affect the risk of developing multiple sclerosis (MS) …

High sodium intake increases blood pressure and risk of kidney disease. From the Science of Salt: A regularly updated systematic review of salt and health outcomes …

D Malta, KS Petersen, C Johnson… - The Journal of …, 2018 - Wiley Online Library
The purpose of this review was to identify, summarize, and critically appraise studies on
dietary salt and health outcomes that were published from August 2016 to March 2017. The …

The role of sodium in modulating immune cell function

N Wilck, A Balogh, L Markó, H Bartolomaeus… - Nature Reviews …, 2019 - nature.com
Sodium intake is undoubtedly indispensable for normal body functions but can be
detrimental when taken in excess of dietary requirements. The consequences of excessive …

The role of dietary sodium in autoimmune diseases: The salty truth

K Sharif, H Amital, Y Shoenfeld - Autoimmunity reviews, 2018 - Elsevier
Autoimmune diseases are a group of heterogeneous condition that occur secondary to the
intrinsic loss of tolerance to self-antigens. In genetically susceptible individuals, the complex …

The modulatory effect of high salt on immune cells and related diseases

X Li, A Alu, Y Wei, X Wei, M Luo - Cell proliferation, 2022 - Wiley Online Library
Background The adverse effect of excessive salt intake has been recognized in decades.
Researchers have mainly focused on the association between salt intake and hypertension …

Contribution of dietary intake to relapse rate in early paediatric multiple sclerosis

S Azary, T Schreiner, J Graves, A Waldman… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective The role of diet in multiple sclerosis (MS) course remains largely unknown.
Children with MS have a higher relapse rate compared with MS in adults. Thus, studying the …

The role of nutritional lifestyle and physical activity in multiple sclerosis pathogenesis and management: a narrative review

S Fanara, M Aprile, S Iacono, G Schirò, A Bianchi… - Nutrients, 2021 - mdpi.com
Studies on the role of nutritional factors and physical activity (PA) in the pathogenesis of
multiple sclerosis (MS) go back a long time. Despite the intrinsic difficulty of studying their …