Post-translational modifications of the protein termini

L Chen, A Kashina - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Post-translational modifications (PTM) involve enzyme-mediated covalent addition of
functional groups to proteins during or after synthesis. These modifications greatly increase …

NATs at a glance

H Aksnes, N McTiernan, T Arnesen - Journal of Cell Science, 2023 - journals.biologists.com
Most proteins receive an acetyl group at the N terminus while in their nascency as the result
of modification by co-translationally acting N-terminal acetyltransferases (NATs). The N …

Protein N-terminal acetylation: structural basis, mechanism, versatility, and regulation

S Deng, R Marmorstein - Trends in biochemical sciences, 2021 - cell.com
N-terminal acetylation (NTA) is one of the most widespread protein modifications, which
occurs on most eukaryotic proteins, but is significantly less common on bacterial and …

Cytosolic actin isoforms form networks with different rheological properties that indicate specific biological function

P Nietmann, K Kaub, A Suchenko, S Stenz… - Nature …, 2023 - nature.com
The implications of the existence of different actins expressed in epithelial cells for network
mechanics and dynamics is investigated by microrheology and confocal imaging. γ-actin …

A solution to the long-standing problem of actin expression and purification

RH Ceron, PJ Carman, G Rebowski… - Proceedings of the …, 2022 - National Acad Sciences
Actin is the most abundant protein in the cytoplasm of eukaryotic cells and interacts with
hundreds of proteins to perform essential functions, including cell motility and cytokinesis …

Novel Au carbene complexes as promising multi-target agents in breast cancer treatment

J Ceramella, A Mariconda, M Sirignano, D Iacopetta… - Pharmaceuticals, 2022 - mdpi.com
Over the past decade, metal complexes based on N-heterocyclic carbenes (NHCs) have
attracted great attention due to their wide and exciting applications in material sciences and …

Profilin: many facets of a small protein

RJ Davey, PDJ Moens - Biophysical Reviews, 2020 - Springer
Profilin is a ubiquitously expressed protein well known as a key regulator of actin
polymerisation. The actin cytoskeleton is involved in almost all cellular processes including …

[HTML][HTML] Purification of modified mammalian actin isoforms for in vitro reconstitution assays

DJ Kast, S Jansen - European journal of cell biology, 2023 - Elsevier
In vitro reconstitution assays using purified actin have greatly improved our understanding of
cytoskeletal dynamics and their regulation by actin-binding proteins. However, early …

Posttranslational modifications of the cytoskeleton

B MacTaggart, A Kashina - Cytoskeleton, 2021 - Wiley Online Library
The cytoskeleton plays important roles in many essential processes at the cellular and
organismal levels, including cell migration and motility, cell division, and the establishment …

Mythical origins of the actin cytoskeleton

C Akıl, Y Kitaoku, LT Tran, D Liebl, H Choe… - Current Opinion in Cell …, 2021 - Elsevier
The origin of the eukaryotic cell is one of the greatest mysteries in modern biology.
Eukaryotic-wide specific biological processes arose in the lost ancestors of eukaryotes …