Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Rubella

N Lambert, P Strebel, W Orenstein, J Icenogle… - The Lancet, 2015 - thelancet.com
Rubella remains an important pathogen worldwide, with roughly 100 000 cases of
congenital rubella syndrome estimated to occur every year. Rubella-containing vaccine is …

Personalized vaccinology: a review

GA Poland, IG Ovsyannikova, RB Kennedy - Vaccine, 2018 - Elsevier
At the current time, the field of vaccinology remains empirical in many respects. Vaccine
development, vaccine immunogenicity, and vaccine efficacy have, for the most part …

Immune system targeting by biodegradable nanoparticles for cancer vaccines

JM Silva, M Videira, R Gaspar, V Préat… - Journal of controlled …, 2013 - Elsevier
The concept of therapeutic cancer vaccines is based on the activation of the immune system
against tumor cells after the presentation of tumor antigens. Nanoparticles (NPs) have …

An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines

F Bayani, NS Hashkavaei, S Arjmand, S Rezaei… - Progress in Biophysics …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that
has caused the recent coronavirus disease (COVID-19) global pandemic. The current …

[HTML][HTML] Current challenges in vaccinology

RB Kennedy, IG Ovsyannikova, P Palese… - Frontiers in …, 2020 - frontiersin.org
The development of vaccines, which prime the immune system to respond to future
infections, has led to global declines in morbidity and mortality from dreadful infectious …

[HTML][HTML] Vaccines: from empirical development to rational design

C Rueckert, CA Guzmán - PLoS pathogens, 2012 - journals.plos.org
Infectious diseases are responsible for an overwhelming number of deaths worldwide and
their clinical management is often hampered by the emergence of multi-drug-resistant …

[HTML][HTML] New approaches to understanding the immune response to vaccination and infection

D Furman, MM Davis - Vaccine, 2015 - Elsevier
The immune system is a network of specialized cell types and tissues that communicates via
cytokines and direct contact, to orchestrate specific types of defensive responses. Until …

Exploring the cancer-testis antigen BORIS to design a novel multi-epitope vaccine against breast cancer based on immunoinformatics approaches

E Mahdevar, A Safavi, A Abiri, A Kefayat… - Journal of …, 2022 - Taylor & Francis
Recently, cancer immunotherapy has gained lots of attention to replace the current
chemoradiation approaches and multi-epitope cancer vaccines are manifesting as the next …

Understanding the immune response to seasonal influenza vaccination in older adults: a systems biology approach

ND Lambert, IG Ovsyannikova, VS Pankratz… - Expert review of …, 2012 - Taylor & Francis
Annual vaccination against seasonal influenza is recommended to decrease disease-
related mortality and morbidity. However, one population that responds suboptimally to …