Polycystic kidney disease is typified by cysts in the kidney and extra-renal manifestations
including hypertension and heart failure. The main genetic underpinning this disease are …

Autosomal dominant polycystic kidney disease, autosomal recessive polycystic kidney
disease, and nephronophthisis are hereditary disorders with the occurrence of numerous …

Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disease
characterized by progressive enlargement of fluid-filled cysts derived from renal tubular …

The matrix metalloproteinase MMP9 influences cellular morphology and function, and plays
important roles in organogenesis and disease. It exerts both protective and deleterious …

Background Notch signaling, a conserved mechanism of cell-to-cell communication, plays a
crucial role in regulating cellular processes such as proliferation and differentiation in a …

The kidney epithelial barrier has multifaceted functions in body fluids, electrolyte
homeostasis, and urine production. The renal epithelial barrier (REB) frequently faces and …

Crizotinib is a tyrosine kinase inhibitor that has been found to be effective in the treatment of
c-ros oncogene 1-positive non-small cell lung cancer. Although this targeted agent for …

The kidney epithelial barrier has multifaceted functions in body fluids, electrolyte
homeostasis, and urine production. The renal epithelial barrier (REB) frequently faces and …

In kidney, epithelial barrier has diverse functions in body fluid and electrolyte homeostasis,
and urine production. Maintaining epithelial integrity fundamentally builds up physiological …

Cancer is a significant health burden as the second leading cause of death worldwide.
Metastasis-driven fatality accentuates the need for novel strategies to impede cancer …