Mechanosensing by vascular endothelium

XR Lim, OF Harraz - Annual Review of Physiology, 2024 - annualreviews.org
Mechanical forces influence different cell types in our bodies. Among the earliest forces
experienced in mammals is blood movement in the vascular system. Blood flow starts at the …

3D bioprinting of complex tissues in vitro: state-of-the-art and future perspectives

Y Xiang, K Miller, J Guan, W Kiratitanaporn, M Tang… - Archives of …, 2022 - Springer
The pharmacology and toxicology of a broad variety of therapies and chemicals have
significantly improved with the aid of the increasing in vitro models of complex human …

The role of PLVAP in endothelial cells

L Denzer, W Muranyi, H Schroten, C Schwerk - Cell and Tissue Research, 2023 - Springer
Endothelial cells play a major part in the regulation of vascular permeability and
angiogenesis. According to their duty to fit the needs of the underlying tissue, endothelial …

Vascular organoids: unveiling advantages, applications, challenges, and disease modelling strategies

H Naderi-Meshkin, VA Cornelius… - Stem Cell Research & …, 2023 - Springer
Understanding mechanisms and manifestations of cardiovascular risk factors, including
diabetes, on vascular cells such as endothelial cells, pericytes, and vascular smooth muscle …

[HTML][HTML] Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skin

Q Li, Z Zhu, L Wang, Y Lin, H Fang, J Lei, T Cao… - Theranostics, 2021 - ncbi.nlm.nih.gov
Vascular endothelial cells (ECs) are increasingly recognized as active players in
intercellular crosstalk more than passive linings of a conduit for nutrition delivery. Yet, their …

The multifaceted roles of the adipose tissue vasculature

A Ioannidou, RM Fisher, CE Hagberg - Obesity Reviews, 2022 - Wiley Online Library
The prevalence of obesity and its associated pathologies continue to increase, which has
led to a renewed interest in our major weight‐regulating organ, the white adipose tissue. It …

PIEZO Ion Channels in Cardiovascular Functions and Diseases

B Coste, P Delmas - Circulation Research, 2024 - Am Heart Assoc
The cardiovascular system provides blood supply throughout the body and as such is
perpetually applying mechanical forces to cells and tissues. Thus, this system is primed with …

The endothelium at the interface between tissues and Staphylococcus aureus in the bloodstream

P Speziale, TJ Foster, CR Arciola - Clinical Microbiology Reviews, 2025 - journals.asm.org
Staphylococcus aureus is a major human pathogen. It can cause many types of infections, in
particular bacteremia, which frequently leads to infective endocarditis, osteomyelitis, sepsis …

hPSC-derived lung organoids: Potential opportunities and challenges

X Du, Y Dong, W Li, Y Chen - Heliyon, 2023 - cell.com
Three-dimensional hPSC-derived lung organoids resemble the fetal lung stage, making
them an excellent model for studying human lung development. However, current hPSC …

[HTML][HTML] Dynamics of endothelial cell diversity and plasticity in Health and Disease

A Larionov, CM Hammer, K Fiedler, L Filgueira - Cells, 2024 - mdpi.com
Endothelial cells (ECs) are vital structural units of the cardiovascular system possessing two
principal distinctive properties: heterogeneity and plasticity. Endothelial heterogeneity is …