Severe cutaneous adverse reactions

SI Hung, M Mockenhaupt, KG Blumenthal… - Nature Reviews …, 2024 - nature.com
Severe cutaneous adverse reactions (SCARs), which include Stevens–Johnson syndrome
and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also …

Recent progress in Stevens–Johnson syndrome/toxic epidermal necrolysis: diagnostic criteria, pathogenesis and treatment

N Hama, S Aoki, CB Chen, A Hasegawa… - British Journal of …, 2025 - academic.oup.com
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) represent a severe
spectrum of rare mucocutaneous reactions that are primarily drug-induced and …

Worldwide prevalence of antibiotic-associated Stevens-Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis

EY Lee, C Knox, EJ Phillips - JAMA dermatology, 2023 - jamanetwork.com
Importance Antibiotics are an important risk for Stevens-Johnson syndrome and toxic
epidermal necrolysis (SJS/TEN), which are the most severe types of drug hypersensitivity …

[HTML][HTML] NSAID (nonsteroidal anti-inflammatory drugs) Induced Stevens Johnson Syndrome in a 50-year-old woman: A case study

N Faraji, R Goli, P Mohsennezhad, Y Mohammadpour… - Toxicology Reports, 2024 - Elsevier
Abstract Stevens-Johnson Syndrome (SJS) is a severe and rare adverse drug reaction
associated with significant morbidity and mortality. Although SJS is commonly triggered by …

Evaluation of plasmapheresis vs immunoglobulin as first treatment after ineffective systemic corticosteroid therapy for patients with Stevens-Johnson syndrome and …

Y Miyamoto, H Ohbe, R Kumazawa, H Matsui… - JAMA …, 2023 - jamanetwork.com
Importance Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are
severe cutaneous adverse reactions, and patients with SJS/TEN frequently require intensive …

Correlations between histopathologic findings, serum biomarker levels, and clinical outcomes in Stevens–Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)

D Chuenwipasakul, C Washrawirul, R Panpruk… - Scientific Reports, 2023 - nature.com
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe
dermatological emergencies. The role of cytokines and chemokines in the pathogenesis …

Stevens-Johnson syndrome and toxic epidermal necrolysis: 11-year retrospective experience in a high-complexity tertiary hospital in Milan, Italy

JW Schroeder, V Caputo, S Guida, F Conte… - Clinics in …, 2023 - Elsevier
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe drug-
induced hypersensitivity reactions characterized by widespread epidermal necrosis, mucous …

Scoring assessments in Stevens-Johnson syndrome and toxic epidermal necrolysis

AS Dobry, S Himed, M Waters… - Frontiers in Medicine, 2022 - frontiersin.org
Epidermal necrolysis, the unifying term for Stevens-Johnson syndrome (SJS) and toxic
epidermal necrolysis (TEN), is a severe cutaneous drug reaction associated with high …

[HTML][HTML] Genetic association of beta-lactams-induced hypersensitivity reactions: A systematic review of genome-wide evidence and meta-analysis of candidate genes

L Lumkul, P Wongyikul, P Kulalert… - World Allergy …, 2023 - Elsevier
Abstract Importance Beta-lactams (BLs) are the most prescribed antibiotics, being the most
frequent cause of drug allergy. However, the association between BL allergy and genetic …

Effectiveness and Safety of Early Short-Course, Moderate-to High-Dose Glucocorticoids for the Treatment of Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis …

Z Ye, C Li, H Zhang, C Zhang, X Lu - Clinical, Cosmetic and …, 2022 - Taylor & Francis
Objective To summarise the clinical characteristics of patients with Stevens–Johnson
syndrome/toxic epidermal necrolysis syndrome (SJS/TEN) and analyse the efficacy and …