Desmosomes are intercellular adhesion complexes involved in various aspects of epithelial
pathophysiology, including tissue homeostasis, morphogenesis, and disease development …

Background Gene expression studies are increasingly used to provide valuable information
on the diagnosis and prognosis of human cancers. Also, for in vitro and in vivo experimental …

Abstract Purpose Desmoglein-2 (Dsg2) is a cell adhesion protein of the cadherin
superfamily. Altered Dsg2 expression is associated with tumorigenesis. This study …

The ability to maintain cell‐cell adhesion is crucial for tissue integrity and organization.
Accordingly, loss of cohesiveness plays a critical role in cancer invasion and metastasis …

The availability of data from profiling of cancer patients with multiomics is rapidly increasing.
However, integrative analysis of such data for personalized target identification is not trivial …

Background: Exploration of serum biomarkers for early detection of upper gastrointestinal
cancer is required. Here, we aimed to evaluate the diagnostic potential of serum desmoglein …

Desmoglein 3 is one of seven desmosomal cadherins that mediate cell-cell adhesion in
desmosomes. Desmosomes are the intercellular junctional complexes that anchor the …

Abstract Desmoglein-3 (Dsg3) is a transmembrane glycoprotein which is preferably found in
desmosomes of keratinocytes in squamous epithelium. Both loss and upregulation of Dsg3 …

The tyrosine kinase human epidermal growth factor receptor 2 (HER2) gene is amplified in
approximately 20% of human breast cancers and is associated with an aggressive clinical …

Desmoglein-2 (DSG2) is a calcium-binding single pass transmembrane glycoprotein and a
member of the large cadherin family. Until recently, DSG2 was thought to only function as a …