Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …

Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Activation of the innate immune STimulator of INterferon Genes (STING) pathway potentiates
antitumour immunity, but systemic delivery of STING agonists to tumours is challenging. We …

Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …

Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …

Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

Abstract mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-
19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …

We designed a unique nanocapsule for efficient single CRISPR-Cas9 capsuling,
noninvasive brain delivery and tumor cell targeting, demonstrating an effective and safe …

There is growing need for a safe, efficient, specific and non-pathogenic means for delivery of
gene therapy materials. Nanomaterials for nucleic acid delivery offer an unprecedented …

Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …