Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Applications of sub-micron low-boiling point phase change contrast agents for ultrasound imaging and therapy

PG Durham, PA Dayton - Current Opinion in Colloid & Interface Science, 2021 - Elsevier
Phase change contrast agents (PCCAs) have been studied in the medical ultrasound field
for nearly three decades. Their ability to convert from a liquid core droplet to an acoustically …

Fast acoustic wave sparsely activated localization microscopy: Ultrasound super-resolution using plane-wave activation of nanodroplets

G Zhang, S Harput, H Hu… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Localization-based ultrasound super-resolution imaging using microbubble contrast agents
and phase-change nanodroplets has been developed to visualize microvascular structures …

From micro-to nano-multifunctional theranostic platform: effective ultrasound imaging is not just a matter of scale

S Zullino, M Argenziano, I Stura, C Guiot… - Molecular …, 2018 - journals.sagepub.com
Ultrasound Contrast Agents (UCAs) consisting of gas-filled-coated Microbubbles (MBs) with
diameters between 1 and 10 µm have been used for a number of decades in diagnostic …

Novel method for the formation of monodisperse superheated perfluorocarbon nanodroplets as activatable ultrasound contrast agents

C de Gracia Lux, AM Vezeridis, J Lux, AM Armstrong… - RSC …, 2017 - pubs.rsc.org
Microbubble (MB) contrast agents have positively impacted the clinical ultrasound (US)
community worldwide. Their use in molecular US imaging applications has been hindered …

Seeing the invisible—ultrasound molecular imaging

A Kosareva, L Abou-Elkacem, S Chowdhury… - Ultrasound in medicine …, 2020 - Elsevier
Ultrasound molecular imaging has been developed in the past two decades with the goal of
non-invasively imaging disease phenotypes on a cellular level not depicted on anatomic …

Contrast ultrasound, Sonothrombolysis and Sonoperfusion in cardiovascular disease: Shifting to Theragnostic clinical trials

S El Kadi, TR Porter, NJW Verouden… - Cardiovascular …, 2022 - jacc.org
Contrast ultrasound has a variety of applications in cardiovascular medicine, both in
diagnosing cardiovascular disease as well as providing prognostic information …

Vaporization detection imaging: A technique for imaging low-boiling-point phase-change contrast agents with a high depth of penetration and contrast-to-tissue ratio

JD Rojas, PA Dayton - Ultrasound in Medicine & Biology, 2019 - Elsevier
Phase-change contrast agents (PCCAs) possess advantages over microbubble contrast
agents, such as the ability to extravasate and circulate longer in the vasculature that could …

Imaging of vaporised sub-micron phase change contrast agents with high frame rate ultrasound and optics

S Lin, G Zhang, A Jamburidze, M Chee… - Physics in Medicine …, 2018 - iopscience.iop.org
Phase-change ultrasound contrast agent (PCCA), or nanodroplet, shows promise as an
alternative to the conventional microbubble agent over a wide range of diagnostic …

Detecting insulitis in type 1 diabetes with ultrasound phase-change contrast agents

DG Ramirez, M Ciccaglione… - Proceedings of the …, 2021 - National Acad Sciences
Type 1 diabetes (T1D) results from immune infiltration and destruction of insulin-producing β
cells within the pancreatic islets of Langerhans (insulitis). Early diagnosis during …