Matrix metalloproteinases in dental and periodontal tissues and their current inhibitors: Developmental, degradational and pathological aspects

M Elgezawi, R Haridy, K Almas, MA Abdalla… - International journal of …, 2022 - mdpi.com
Objectives: This review article aims to describe some of the roles of Matrix
metalloproteinases (MMPs) in enamel, dentine, dental caries, hybrid layer degradation, pulp …

Matrix Metalloproteinases in Oral Health—Special Attention on MMP-8

T Atanasova, T Stankova, A Bivolarska, T Vlaykova - Biomedicines, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are a large family of Ca2+ and Zn2+ dependent
proteolytic enzymes, able to cleave the various components of the extracellular matrix …

Organoids from mouse molar and incisor as new tools to study tooth-specific biology and development

F Hermans, L Hemeryck, C Bueds, MT Pereiro… - Stem Cell Reports, 2023 - cell.com
Organoid models provide powerful tools to study tissue biology and development in a dish.
Presently, organoids have not yet been developed from mouse tooth. Here, we established …

Interactions with the aquaporin 5 gene increase the susceptibility to molar-incisor hypomineralization

L Pang, X Li, K Wang, Y Tao, T Cui, Q Xu, H Lin - Archives of oral biology, 2020 - Elsevier
Objective The aim of this study was to evaluate whether individual genetic factors involved in
amelogenesis, the immune response and water channel proteins may increase the …

In silico study of some natural anthraquinones on matrix metalloproteinase inhibition

A Taherkhani, S Moradkhani, A Orangi… - Research Journal of …, 2021 - rjpharmacognosy.ir
Background and objectives: Matrix metalloproteinase-13 (MMP-13) is a proteolytic enzyme
playing an important role in the activation of the MMP cascade, which seems to be vital in …

The critical role of MMP13 in regulating tooth development and reactionary dentinogenesis repair through the wnt signaling pathway

HF Duncan, Y Kobayashi, Y Yamauchi… - Frontiers in Cell and …, 2022 - frontiersin.org
Matrix-metalloproteinase-13 (MMP13) is important for bone formation and remodeling;
however, its role in tooth development remains unknown. To investigate this, MMP13 …

Maxillary incisor enamel defects in individuals born with cleft lip/palate

JR Lavôr, RHW Lacerda, A Modesto, AR Vieira - Plos one, 2020 - journals.plos.org
Cleft lip with or without cleft palate (CLP) is considered the most frequent congenital
malformations of the head and neck, with cleft individuals exhibiting more chances of …

Matrix metalloproteinases gene variants and dental caries in Czech children

P Borilova Linhartova, T Deissova, M Kukletova… - BMC Oral Health, 2020 - Springer
Abstract Background Matrix metalloproteinases (MMPs) play an important role in tooth
formation and the mineralization of dental tissue. The aim of the study was to analyse Czech …

[HTML][HTML] Association of genetic variants in enamel-formation genes with dental caries: A meta-and gene-cluster analysis

X Li, D Liu, Y Sun, J Yang, Y Yu - Saudi Journal of Biological Sciences, 2021 - Elsevier
Previous studies have reported the association between multiple genetic variants in the
enamel-formation genes and the risk of dental caries with inconsistent results. We performed …

[HTML][HTML] Association of taste receptor gene polymorphisms with dental caries

J Arid, LAA Antunes, LFA Koch, SS Evangelista… - Brazilian Oral …, 2020 - SciELO Brasil
This study was performed to evaluate the interplay between dental caries, nutritional status,
and genetic polymorphisms in TAS1R1 and TAS1R2 (taste receptor, type 1, member 1 and …