The discovery of somatic cell nuclear transfer proved that somatic cells can carry the same
genetic code as the zygote, and that activating parts of this code are sufficient to reprogram …

The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Juvenile myelomonocytic leukemia (JMML) is a unique, aggressive hematopoietic disorder
of infancy/early childhood caused by excessive proliferation of cells of monocytic and …

Juvenile myelomonocytic leukemia (JMML) is a unique clonal hematopoietic disorder of
early childhood. It is classified as an overlap myeloproliferative/myelodysplastic neoplasm …

Organoids represent one of the most important advancements in the field of stem cells
during the past decade. They are three-dimensional in vitro culturing models that originate …

Together with recent advances in the processing and culture of human tissue,
bioengineering, xenotransplantation and genome editing, Induced pluripotent stem cells …

Organoids derived from adult stem cells (ASCs) and pluripotent stem cells (PSCs) are
important preclinical models for studying cancer and developing therapies. Here, we review …

RAS genes encode a family of 21 kDa proteins that are an essential hub for a number of
survival, proliferation, differentiation and senescence pathways. Signaling of the RAS …

Pediatric leukemia is the single most common malignancy affecting children, representing
up to 30% of all pediatric cancers. Dramatic improvements in survival for acute …

Mesenchymal stem cells (MSC s) are being assessed for ameliorating the severity of graft‐
versus‐host disease, autoimmune conditions, musculoskeletal injuries and cardiovascular …