Is it time to reassess the role of radiotherapy treatment in ovarian cancer?

G Macchia, F Titone, S Restaino, M Arcieri… - Healthcare, 2023 - mdpi.com
With a 5-year survival rate of fewer than 50%, epithelial ovarian carcinoma is the most fatal
of the gynecologic cancers. Each year, an estimated 22,000 women are diagnosed with the …

Efficacy and safety of recombinant human adenovirus type 5 (H101) in persistent, recurrent, or metastatic gynecologic malignancies: a retrospective study

J Zhang, Q Zhang, Z Liu, J Wang, F Shi, J Su… - Frontiers in …, 2022 - frontiersin.org
Background To assess the efficacy and safety of recombinant human adenovirus type 5
(H101) in patients with persistent, recurrent, or metastatic gynecologic malignancies …

Stereotactic Body Radiation Therapy: Opportunities and Limitations

EM Jaworski, TS Lawrence - The Cancer Journal, 2024 - journals.lww.com
According to American Society for Radiation Oncology (ASTRO's) 2020 Model Policies,
stereotactic body radiation therapy (SBRT) comprises a course of ablative radiation …

Efficacy and safety of stereotactic body radiation therapy in oligometastatic uterine cancer (MITO-RT2/RAD): a large, real-world study in collaboration with Italian …

G Macchia, D Pezzulla, M Campitelli, C Laliscia… - International Journal of …, 2023 - Elsevier
Purpose This retrospective, multicenter study analyzes the efficacy and safety of stereotactic
body radiation therapy in a large cohort of patients with oligometastatic/persistent/recurrent …

Evaluation of auto-segmentation for brachytherapy of postoperative cervical cancer using deep learning-based workflow

J Wang, Y Chen, Y Tu, H Xie, Y Chen… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. The purpose of this study was to evaluate the accuracy of brachytherapy (BT)
planning structures derived from Deep learning (DL) based auto-segmentation compared …

[HTML][HTML] Global proteomics indicates subcellular-specific anti-ferroptotic responses to ionizing radiation

JA Christopher, LM Breckels, OM Crook… - Molecular & Cellular …, 2025 - Elsevier
Highlights•Protein trafficking is essential for quick cellular response to ionizing
radiation.•Subcellular proteomics detected hundreds of these potential trafficking events.•Of …

125I seed brachytherapy for non-central pelvic recurrence of cervical cancer after external beam radiotherapy

X Di, Z Gao, H Yu, X Liu, J Zhao, J Wang, H Zhang - Radiation Oncology, 2024 - Springer
Objective To investigate the efficacy of 125I seed brachytherapy for non-central pelvic
recurrence of cervical cancer after external beam radiotherapy, and to analyze the clinical …

Quality assessment of automatically planned O‐Ring linac SBRT plans for pelvic lymph node metastases, finding the optimal minimum target size by comparison with …

KVD Hernández, S Unterkirhers… - Journal of Applied …, 2023 - Wiley Online Library
Purpose The purpose of this study is to assess the quality of automatic planned O‐Ring
Halcyon linac SBRT plans for pelvic lymph node metastases and to establish an absolute …

Efficacy of stereotactic body radiotherapy and response prediction using artificial intelligence in oligometastatic gynaecologic cancer

G Macchia, S Cilla, D Pezzulla, M Campitelli… - Gynecologic …, 2024 - Elsevier
Purpose We present a large real-world multicentric dataset of ovarian, uterine and cervical
oligometastatic lesions treated with SBRT exploring efficacy and clinical outcomes. In …

[HTML][HTML] Recurrent Gynecological Tumors in Previously Irradiated Patients. Does Re-Irradiation with Stereotactic Body Radiotherapy Have a Role? A Systematic …

A Pontoriero, P Critelli, A Bosurgi… - Clinical and …, 2023 - imrpress.com
Background: Re-irradiation of patients with previously irradiated gynecological tumors
represents one of the hot topics of modern oncology. It is generally performed using …