Immune system abnormalities in schizophrenia: an integrative view and translational perspectives
EA Ermakov, MM Melamud, VN Buneva… - Frontiers in …, 2022 - frontiersin.org
The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …
pathogens. Any pathological conditions are reflected in anomalies in the immune system …
Immune dysfunction in schizophrenia spectrum disorders
SS Gangadin, AD Enthoven… - Annual review of …, 2024 - annualreviews.org
Evidence from epidemiological, clinical, and biological research resulted in the immune
hypothesis: the hypothesis that immune system dysfunction is involved in the …
hypothesis: the hypothesis that immune system dysfunction is involved in the …
Neuroinflammation in schizophrenia: the key role of the WNT/β-catenin pathway
A Vallée - International Journal of Molecular Sciences, 2022 - mdpi.com
Schizophrenia is a very complex syndrome involving widespread brain multi-
dysconnectivity. Schizophrenia is marked by cognitive, behavioral, and emotional …
dysconnectivity. Schizophrenia is marked by cognitive, behavioral, and emotional …
The role of cytokines in the pathogenesis of schizophrenia
B Dawidowski, A Górniak, P Podwalski… - Journal of Clinical …, 2021 - mdpi.com
Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …
body of evidence implicates immunologic dysfunction as the key element in its …
Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis
The development of effective combined anti-retroviral therapy (cART) led to a significant
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …
[HTML][HTML] The role of the gut microbiome in the development of schizophrenia
Schizophrenia is a heterogeneous neurodevelopmental disorder involving the convergence
of a complex and dynamic bidirectional interaction of genetic expression and the …
of a complex and dynamic bidirectional interaction of genetic expression and the …
An integrative approach to neuroinflammation in psychiatric disorders and neuropathic pain
DI Lurie - Journal of experimental neuroscience, 2018 - journals.sagepub.com
Neuroinflammation is a complex process involving both the peripheral circulation and the
Central Nervous System (CNS) and is considered to underlie many CNS disorders including …
Central Nervous System (CNS) and is considered to underlie many CNS disorders including …
Large-scale evidence for an association between peripheral inflammation and white matter free water in schizophrenia and healthy individuals
Introduction Clarifying the role of neuroinflammation in schizophrenia is subject to its
detection in the living brain. Free-water (FW) imaging is an in vivo diffusion-weighted …
detection in the living brain. Free-water (FW) imaging is an in vivo diffusion-weighted …
Constructing the immune signature of schizophrenia for clinical use and research; an integrative review translating descriptives into diagnostics
Schizophrenia is considered a syndrome comprised by several disease phenotypes,
covering a range of underlying pathologies. One of these disease mechanisms seems to …
covering a range of underlying pathologies. One of these disease mechanisms seems to …
[HTML][HTML] The neural, stress hormone and inflammatory correlates of childhood deprivation and threat in psychosis: A systematic review
Childhood adversity increases the risk of developing psychosis, but the biological
mechanisms involved are unknown. Disaggregating early adverse experiences into core …
mechanisms involved are unknown. Disaggregating early adverse experiences into core …