[HTML][HTML] The essential role of exercise in the management of type 2 diabetes

JP Kirwan, J Sacks, S Nieuwoudt - Cleveland Clinic journal of …, 2017 - ncbi.nlm.nih.gov
Exercise is typically one of the first management strategies advised for patients newly
diagnosed with type 2 diabetes. Together with diet and behavior modification, exercise is an …

Glucose transporters in the small intestine in health and disease

H Koepsell - Pflügers Archiv-European Journal of Physiology, 2020 - Springer
Absorption of monosaccharides is mainly mediated by Na+-d-glucose cotransporter SGLT1
and the facititative transporters GLUT2 and GLUT5. SGLT1 and GLUT2 are relevant for …

Pediatric obesity—assessment, treatment, and prevention: an Endocrine Society clinical practice guideline

DM Styne, SA Arslanian, EL Connor… - The Journal of …, 2017 - academic.oup.com
Abstract Cosponsoring Associations: The European Society of Endocrinology and the
Pediatric Endocrine Society. This guideline was funded by the Endocrine Society. Objective …

Differential adaptation of human gut microbiota to bariatric surgery–induced weight loss: links with metabolic and low-grade inflammation markers

JP Furet, LC Kong, J Tap, C Poitou, A Basdevant… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Obesity alters gut microbiota ecology and associates with low-grade
inflammation in humans. Roux-en-Y gastric bypass (RYGB) surgery is one of the most …

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

A Abizaid, ZW Liu, ZB Andrews… - The Journal of …, 2006 - Am Soc Clin Investig
The gut hormone ghrelin targets the brain to promote food intake and adiposity. The ghrelin
receptor growth hormone secretagogue 1 receptor (GHSR) is present in hypothalamic …

Weight loss, appetite suppression, and changes in fasting and postprandial ghrelin and peptide-YY levels after Roux-en-Y gastric bypass and sleeve gastrectomy: a …

SN Karamanakos, K Vagenas, F Kalfarentzos… - Annals of …, 2008 - journals.lww.com
Background: Bariatric surgery is currently the most effective treatment in morbidly obese
patients, leading to durable weight loss. Objective: In this prospective double blind study, we …

Gut hormones and the regulation of energy homeostasis

KG Murphy, SR Bloom - Nature, 2006 - nature.com
Food intake, energy expenditure and body adiposity are homeostatically regulated. Central
and peripheral signals communicate information about the current state of energy balance to …

The defence of body weight: a physiological basis for weight regain after weight loss

P Sumithran, J Proietto - Clinical Science, 2013 - portlandpress.com
Although weight loss can usually be achieved by restricting food intake, the majority of
dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the …

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

ME Patti, SM Houten, AC Bianco, R Bernier… - …, 2009 - Wiley Online Library
The multifactorial mechanisms promoting weight loss and improved metabolism following
Roux‐en‐Y gastric bypass (GB) surgery remain incompletely understood. Recent rodent …

The gut-brain axis, the human gut microbiota and their integration in the development of obesity

ES Bliss, E Whiteside - Frontiers in physiology, 2018 - frontiersin.org
Obesity is a global epidemic, placing socioeconomic strain on public healthcare systems,
especially within the so-called Western countries, such as Australia, United States, United …