Colorectal cancer in inflammatory bowel disease: mechanisms and management

SC Shah, SH Itzkowitz - Gastroenterology, 2022 - Elsevier
Patients with inflammatory bowel disease (IBD) are at increased risk of developing
colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic …

[HTML][HTML] Prognostic factors for advanced colorectal neoplasia in inflammatory bowel disease: systematic review and meta-analysis

AM Wijnands, ME de Jong, MWMD Lutgens… - Gastroenterology, 2021 - Elsevier
Background and Aims Patients with inflammatory bowel disease (IBD) have an increased
risk of colorectal cancer (CRC). We performed a systematic review and meta-analysis to …

ACG clinical guideline: ulcerative colitis in adults

DT Rubin, AN Ananthakrishnan… - Official journal of the …, 2019 - journals.lww.com
Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the
preferred approach to the management of adults with UC and represent the official practice …

ECCO guidelines on inflammatory bowel disease and malignancies

H Gordon, L Biancone, G Fiorino… - Journal of Crohn's …, 2023 - academic.oup.com
This guideline is the second European Crohn's and Colitis Organisation [ECCO] evidence-
based consensus on inflammatory bowel disease [IBD] and malignancy, and is an update …

What does disease progression look like in ulcerative colitis, and how might it be prevented?

NK Cleveland, J Torres, DT Rubin - Gastroenterology, 2022 - Elsevier
Ulcerative colitis (UC) has been characterized by inflammation limited to the mucosa.
Although sustained and durable remission has been associated with mucosal healing, the …

[HTML][HTML] Disease monitoring in inflammatory bowel disease: evolving principles and possibilities

N Plevris, CW Lees - Gastroenterology, 2022 - Elsevier
Inflammatory bowel disease is a progressive and debilitating condition. Early and effective
treatment utilizing a treat to target approach is key in improving patient outcomes. Therefore …

A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8+ T cells in …

L Wang, L Tang, Y Feng, S Zhao, M Han, C Zhang… - Gut, 2020 - gut.bmj.com
Objective Gut microbiota have been linked to inflammatory bowel disease (IBD) and
colorectal cancer (CRC). Akkermansia muciniphila (A. muciniphila) is a gram-negative …

An update on current pharmacotherapeutic options for the treatment of ulcerative colitis

F Ferretti, R Cannatelli, MC Monico, G Maconi… - Journal of Clinical …, 2022 - mdpi.com
The main goals of Ulcerative Colitis (UC) treatment are to both induce and maintain the
clinical and endoscopic remission of disease, reduce the incidence of complications such as …

Colorectal cancer in ulcerative colitis: mechanisms, surveillance and chemoprevention

W Li, T Zhao, D Wu, J Li, M Wang, Y Sun, S Hou - Current Oncology, 2022 - mdpi.com
Patients with ulcerative colitis (UC) are at a two-to three-fold increased risk of developing
colorectal cancer (CRC) than the general population based on population-based data. UC …

ECCO position paper: harmonization of the approach to ulcerative colitis histopathology

F Magro, G Doherty, L Peyrin-Biroulet… - Journal of Crohn's …, 2020 - academic.oup.com
Currently, the main targets of drug therapy for ulcerative colitis [UC] are endoscopic and
clinical remission. However, there is active discussion about the additional advantages of …