Leveraging transformers‐based language models in proteome bioinformatics

NQK Le - Proteomics, 2023 - Wiley Online Library
In recent years, the rapid growth of biological data has increased interest in using
bioinformatics to analyze and interpret this data. Proteomics, which studies the structure …

UniDL4BioPep: a universal deep learning architecture for binary classification in peptide bioactivity

Z Du, X Ding, Y Xu, Y Li - Briefings in Bioinformatics, 2023 - academic.oup.com
Identification of potent peptides through model prediction can reduce benchwork in wet
experiments. However, the conventional process of model buildings can be complex and …

D eepafp: an effective computational framework for identifying antifungal peptides based on deep learning

L Yao, Y Zhang, W Li, CR Chung, J Guan… - Protein …, 2023 - Wiley Online Library
Fungal infections have become a significant global health issue, affecting millions
worldwide. Antifungal peptides (AFPs) have emerged as a promising alternative to …

AI Methods for Antimicrobial Peptides: Progress and Challenges

CA Brizuela, G Liu, JM Stokes… - Microbial …, 2025 - Wiley Online Library
Antimicrobial peptides (AMPs) are promising candidates to combat multidrug‐resistant
pathogens. However, the high cost of extensive wet‐lab screening has made AI methods for …

Gr-m6a: prediction of n6-methyladenosine sites in mammals with molecular graph and residual network

S Qiu, R Liu, Y Liang - Computers in Biology and Medicine, 2023 - Elsevier
Abstract RNA N6-methyladenine (m6A), which is produced by the methylation of the N6
position of eukaryotic adenine, is a relatively common post-transcriptional modification on …

iAMP-Attenpred: a novel antimicrobial peptide predictor based on BERT feature extraction method and CNN-BiLSTM-Attention combination model

W Xing, J Zhang, C Li, Y Huo… - Briefings in …, 2024 - academic.oup.com
As a kind of small molecule protein that can fight against various microorganisms in nature,
antimicrobial peptides (AMPs) play an indispensable role in maintaining the health of …

dbAMP 3.0: updated resource of antimicrobial activity and structural annotation of peptides in the post-pandemic era

L Yao, J Guan, P Xie, CR Chung, Z Zhao… - Nucleic Acids …, 2025 - academic.oup.com
Antimicrobial resistance is one of the most urgent global health threats, especially in the post-
pandemic era. Antimicrobial peptides (AMPs) offer a promising alternative to traditional …

Multi-label classification and features investigation of antimicrobial peptides with various functional classes

CR Chung, JT Liou, LC Wu, JT Horng, TY Lee - Iscience, 2023 - cell.com
The challenge of drug-resistant bacteria to global public health has led to increased
attention on antimicrobial peptides (AMPs) as a targeted therapeutic alternative with a lower …

deep-AMPpred: A Deep Learning Method for Identifying Antimicrobial Peptides and Their Functional Activities

J Zhao, H Liu, L Kang, W Gao, Q Lu… - Journal of Chemical …, 2025 - ACS Publications
Antimicrobial peptides (AMPs) are small peptides that play an important role in disease
defense. As the problem of pathogen resistance caused by the misuse of antibiotics …

Diff-AMP: tailored designed antimicrobial peptide framework with all-in-one generation, identification, prediction and optimization

R Wang, T Wang, L Zhuo, J Wei, X Fu… - Briefings in …, 2024 - academic.oup.com
Antimicrobial peptides (AMPs), short peptides with diverse functions, effectively target and
combat various organisms. The widespread misuse of chemical antibiotics has led to …