Actin plays many well-known roles in cells, and understanding any specific role is often
confounded by the overlap of multiple actin-based structures in space and time. Here, we …

Brain computation is metabolically expensive and requires the supply of significant amounts
of energy. Mitochondria are highly specialized organelles whose main function is to …

Damaged mitochondria need to be cleared to maintain the quality of the mitochondrial pool.
Here, we report mitocytosis, a migrasome-mediated mitochondrial quality-control process …

Mitochondria are multifunctional organelles that not only produce energy for the cell, but are
also important for cell signalling, apoptosis and many biosynthetic pathways. In most cell …

Mitochondria are vital organelles in cells, regulating energy metabolism and apoptosis.
Mitochondrial transcellular transfer plays a crucial role during physiological and pathological …

The folded mitochondria inner membrane-cristae is the structural foundation for oxidative
phosphorylation (OXPHOS) and energy production. By mechanically simulating …

Mitochondrial homeostasis requires a dynamic balance of fission and fusion. The actin
cytoskeleton promotes fission, and we found that the mitochondrially localized myosin …

Highlights•Mitochondrial dynamics depend on interactions with the cytoskeleton.•
Interactions with microtubules mediate motility, turnover, and organelle inheritance.• …

Amyotrophic lateral sclerosis (ALS) is a progressive and devastating multifactorial
neurodegenerative disorder. Although the pathogenesis of ALS is still not completely …

Migrasomes are migration‐dependent membrane‐bound vesicular structures that contain
cellular contents and small vesicles. Migrasomes grow on the tips or intersections of the …