Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Neurovascular dysfunction, including blood–brain barrier (BBB) breakdown and cerebral
blood flow (CBF) dysregulation and reduction, are increasingly recognized to contribute to …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

Background Individuals with mild cognitive impairment (MCI) have a substantially increased
risk of developing dementia due to Alzheimer's disease (AD). In this study, we developed a …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Abstract Introduction Alzheimer's Disease Neuroimaging Initiative (ADNI) is now in its 10th
year. The primary objective of the magnetic resonance imaging (MRI) core of ADNI has been …

Executive functioning (EF) is an important cognitive domain that is negatively affected in a
number of neuropsychiatric conditions. Neuroimaging methods have led to insights into the …

Age is the strongest risk factor for sporadic Alzheimer disease (AD), yet the effects of age on
rates of clinical decline and brain atrophy in AD have been largely unexplored. Here, we …

Background: The Montreal Cognitive Assessment (MoCA) is a very widely used test for mild
cognitive impairment. Differing recommendations have been made regarding its utility in …

Vascular risk factors and cerebral blood flow (CBF) reduction have been linked to increased
risk of cognitive impairment and Alzheimer's disease (AD); however the possible moderating …