Abstract The Genitourinary Pathology Society (GUPS) undertook a critical review of the
recent advances in bladder neoplasia with a focus on issues relevant to the practicing …

In the setting of pronounced inflammation, changes in the epithelium may overlap with
neoplasia, often rendering it impossible to establish a diagnosis with certainty in daily …

The bladder working group of the 2013 International Society of Urologic Pathology (ISUP)
Conference on Best Practices Recommendation in the Application of Immunohistochemistry …

Background Daylight‐mediated photodynamic therapy (DL‐PDT) using methyl‐5‐
aminolaevulinate (MAL) is effective for thin, grade I, actinic keratoses (AK). There are no …

Urothelial carcinoma of the bladder and upper tract pose significant diagnostic and
therapeutic challenges. White light endoscopy plays a central role in the management of …

The classification of neoplastic precursor lesions in the urinary tract has evolved slowly with
the gradual accumulation of clinicopathological data. Current nomenclature was codified …

Flat urothelial lesions with atypia may pose significant diagnostic challenges. Given frequent
increased proliferation rates in florid reactive urothelial atypia and limited studies on the …

The concept of a “p53 null phenotype”(complete loss of staining) is well-recognized in the
gynecologic pathology literature, implicitly reflecting that this staining pattern represents a …

Urinary bladder specimens are frequently encountered in the daily practice of surgical
pathologists. The spectrum of pathologic entities encountered in bladder specimens is …

Ancillary testing with immunohistochemistry has shown recent promise in the workup of
equivocal bladder lesions. We read with interest the recent findings of Alston et al., who …