During the past few decades, supercritical fluid (SCF) has emerged as an effective
alternative for many traditional pharmaceutical manufacturing processes. Operating active …

Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

Poor water solubility and poor bioavailability are problems with many pharmaceuticals.
Increasing surface area by micronization is an effective strategy to overcome these …

Micronization is a mechanical and high shearing operation to downsize the particles of food
material to the micron range. Conventionally micronization techniques were employed in …

Carotenoids are lipophilic secondary plant compounds, and their consumption within fruits
and vegetables has been positively correlated with a decreased risk of developing several …

The supercritical antisolvent (SAS) technique has been widely employed in the biomedical
field, including drug delivery, to obtain drug particles or polymer-based systems of …

The solubility and bioavailability of pharmaceutical compounds are increased via size
reduction. The conventional size reduction methods have some disadvantages. The …

Solution enhanced dispersion by supercritical fluids (SEDS) was applied for the production
of lutein/zein nanoparticles. The effects of the process variables on the morphology, drug …

Nanostructured materials have been attracting increased attention for a wide variety of
applications due to their superior properties compared to their bulk counterparts. Current …

In recent years, the demand for nutritive, functional and healthy foods has increased. This
trend has induced the food industry to investigate novel technologies able to produce …