Strecker reaction and α-amino nitriles: Recent advances in their chemistry, synthesis, and biological properties

VV Kouznetsov, CEP Galvis - Tetrahedron, 2018 - Elsevier
Abstract α-Amino nitrile compounds have a profound impact on bio-chemical sciences, as
they have been prepared from inexpensive starting materials and have become valuable …

Organocatalytic synthesis of α-aminonitriles: a review

B Ullah, NK Gupta, Q Ke, N Ullah, X Cai, D Liu - Catalysts, 2022 - mdpi.com
α-Aminonitriles, which have anticancer, antibacterial, antiviral, and antifungal properties,
have played an important role in pharmacology. Furthermore, they can also be used to …

Mandelic acid catalyzed one-pot three-component synthesis of α-aminonitriles and α-aminophosphonates under solvent-free conditions at room temperature

G Kaur, M Shamim, V Bhardwaj, VK Gupta… - Synthetic …, 2020 - Taylor & Francis
A simple, mild, straightforward, efficient and eco-friendly protocol has been developed for
the synthesis of a series of α-aminonitriles via the one-pot three-component Strecker …

Gallic acid grafted to amine‐functionalized magnetic nanoparticles as a proficient catalyst for environmentally friendly synthesis of α‐aminonitriles

A Maleki, S Azadegan, J Rahimi - Applied Organometallic …, 2019 - Wiley Online Library
An effective approach of one‐pot catalytic Strecker reaction between aromatic aldehydes,
aniline or toluidine and trimethylsilyl cyanide in the presence of amine‐functionalized …

l-Proline-catalyzed regioselective C1 arylation of tetrahydroisoquinolines through a multicomponent reaction under solvent-free conditions

I Rahman, B Deka, R Thakuria, ML Deb… - Organic & Biomolecular …, 2020 - pubs.rsc.org
Here we disclose the C1 arylation of tetrahydroisoquinolines (THIQ) through regioselective
C (sp3)–H functionalization using a multicomponent reaction. The reaction was performed …

Synthesis of 2-Vinylindole-3-Acetic Acid Derivatives via Cyanide-Catalyzed Imino-Stetter Reaction

HA Seo, CH Cheon - The Journal of Organic Chemistry, 2016 - ACS Publications
A new method for the synthesis of 2-vinylindole-3-acetic acid derivatives from aldimines,
which are derived from 2-aminocinnamic acid derivatives and α, β-unsaturated aldehydes …

l-Proline catalyzed multicomponent reactions

S Khandelwal, Y Kumar Tailor… - Current …, 2016 - ingentaconnect.com
The multicomponent reactions involving the use of environmentally benign solvents, and
non-toxic, and recyclable organocatalysts require special attention as with such significant …

Application of nature's chiral pool in environmentally sustainable organic synthesis

A Gogoi, Mezhubeinuo, S Nongrum… - Current Organic …, 2021 - benthamdirect.com
Recent years have witnessed a rapid development of environmentally sustainable organic
processes that can stop the eventual depletion of our eco-system with wider implications on …

l-Proline catalyzed domino Michael addition of N-substituted anilines

ML Deb, B Deka, I Rahman, PK Baruah - Tetrahedron Letters, 2018 - Elsevier
Here we report l-proline catalyzed 3-component reaction of indoles, aldehydes and N-
substituted anilines in water as solvent at room temperature for the synthesis of 3-(α, α …

Three helical chain-based 3D coordination polymers: solvent-induced syntheses, tunable structures and catalytic properties for the Strecker reaction

J Chai, P Zhang, X Shi, J Sun, L Wang, Y Fan - CrystEngComm, 2019 - pubs.rsc.org
Three three-dimensional (3D) helical chain-based coordination polymers [Sc
(aip)(OH)·(H2O)] n (1),[Sc2 (aip) 3] n (2) and [Sc2 (nip) 3] n (3)(H2aip= 5-aminoisophthalic …