Hippo pathway is a master regulator of development, cell proliferation, stem cell function,
tissue regeneration, homeostasis, and organ size control. Hippo pathway relays signals from …

Despite many advances, metastatic disease remains essentially uncurable. Thus, there is an
urgent need to better understand mechanisms that promote metastasis, drive tumor …

A fundamental and unresolved question in regenerative biology is how tissues return to
homeostasis after injury. Answering this question is essential for understanding the …

Triple-negative breast cancer (TNBC) and HER2-positive breast cancer are particularly
aggressive and associated with unfavorable prognosis. TNBC lacks effective treatments …

Mechanical cues are crucial for survival, adaptation, and normal homeostasis in virtually
every cell type. The transduction of mechanical messages into intracellular biochemical …

LncRNAs play a pivotal role in the regulation of epigenetic modification, cell cycle,
differentiation, proliferation, migration and other physiological activities. In particular …

The evolutionarily conserved Hippo kinase signaling cascade governs cell proliferation,
tissue differentiation and organ size, and can promote tumor growth and cancer metastasis …

Alzheimer's disease (AD, OMIM: 104300) is an age-related disorder that affects millions of
people. One of the underlying causes of AD is generation of hydrophobic amyloid-beta 42 …

As highly conserved among diverse species, Hippo signaling pathway regulates various
biological processes, including development, cell proliferation, stem cell function, tissue …

Simple Summary The conserved Hippo pathway regulates cell proliferation and apoptosis
via a complex interplay of transcriptional activities, post-translational protein modifications …