Human NK cells: From development to effector functions

AS Perera Molligoda Arachchige - Innate immunity, 2021 - journals.sagepub.com
NK cells are the major lymphocyte subset of the innate immune system that mediates
antiviral and anti-tumor responses. It is well established that they develop mechanisms to …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Memory-like natural killer cells for cancer immunotherapy

M Gang, P Wong, MM Berrien-Elliott… - Seminars in hematology, 2020 - Elsevier
Natural killer (NK) cells are cytotoxic innate lymphoid cells that protect the host from infection
and mediate anti-tumor responses. Classically considered part of the innate immune system …

T cell activation, highly armed cytotoxic cells and a shift in monocytes CD300 receptors expression is characteristic of patients with severe COVID-19

O Zenarruzabeitia, G Astarloa-Pando, I Terren… - Frontiers in …, 2021 - frontiersin.org
COVID-19 manifests with a wide diversity of clinical phenotypes characterized by
dysfunctional and exaggerated host immune responses. Many results have been described …

[图书][B] Clinical hematology and fundamentals of hemostasis

D Harmening - 2024 - books.google.com
A full-color text, lab manual, & atlas—all in one! Here are all the tools medical laboratory
science students need to master the principles of hematology and the fundamentals of …

NK cells in cancer: mechanisms of dysfunction and therapeutic potential

F Portale, D Di Mitri - International Journal of Molecular Sciences, 2023 - mdpi.com
Natural killer cells (NK) are innate lymphocytes endowed with the ability to recognize and kill
cancer cells. Consequently, adoptive transfer of autologous or allogeneic NK cells …

The bone marrow microenvironment mechanisms in acute myeloid leukemia

DB Pimenta, VA Varela, TS Datoguia… - Frontiers in Cell and …, 2021 - frontiersin.org
Bone marrow (BM) is a highly complex tissue that provides important regulatory signals to
orchestrate hematopoiesis. Resident and transient cells occupy and interact with some well …

Molecular regulation of NK cell maturation

J Bi, X Wang - Frontiers in immunology, 2020 - frontiersin.org
Natural killer (NK) cells are innate lymphocytes specialized in immune surveillance against
tumors and infections. To reach their optimal functional status, NK cells must undergo a …

[HTML][HTML] Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D-mediated mechanosensing

B Hu, Y Xin, G Hu, K Li, Y Tan - APL bioengineering, 2023 - pubs.aip.org
Tumor cells metastasize to distant organs mainly via hematogenous dissemination, in which
circulating tumor cells (CTCs) are relatively vulnerable, and eliminating these cells has great …

T cell subsets and natural killer cells in the pathogenesis of nonalcoholic fatty liver disease

YA Gebru, H Gupta, HS Kim, JA Eom, GH Kwon… - International Journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by hepatic
accumulation of excess lipids. T cells are commonly classified into various subsets based on …