Evolution and diversity of immune responses during acute HIV infection

SW Kazer, BD Walker, AK Shalek - Immunity, 2020 - cell.com
Understanding the earliest immune responses following HIV infection is critical to inform
future vaccines and therapeutics. Here, we review recent prospective human studies in at …

Human B-cell subset identification and changes in inflammatory diseases

RL Velounias, TJ Tull - Clinical and experimental immunology, 2022 - academic.oup.com
Our understanding of the B-cell subsets found in human blood and their functional
significance has advanced greatly in the past decade. This has been aided by the evolution …

Naive-and memory-like CD21low B cell subsets share core phenotypic and signaling characteristics in systemic autoimmune disorders

M Freudenhammer, RE Voll, SC Binder… - The Journal of …, 2020 - journals.aai.org
An expansion of CD21 low B cells has been described in a variety of diseases associated
with persistent immune stimulation as in chronic infection, immunodeficiency, or …

HIV‐1 infection of CD4 T cells impairs antigen‐specific B cell function

S Kaw, S Ananth, N Tsopoulidis, K Morath… - The EMBO …, 2020 - embopress.org
Failures to produce neutralizing antibodies upon HIV‐1 infection result in part from B‐cell
dysfunction due to unspecific B‐cell activation. How HIV‐1 affects antigen‐specific B‐cell …

Mucosal‐associated invariant T cells: A cryptic coordinator in HIV‐infected immune reconstitution

B Su, D Kong, X Yang, T Zhang… - Journal of Medical …, 2022 - Wiley Online Library
Human immunodeficiency virus type 1 (HIV‐1) infection causes considerable morbidity and
mortality worldwide. Although antiretroviral therapy (ART) has largely transformed HIV …

Clinical and molecular properties of human immunodeficiency virus-related diffuse large B-cell lymphoma

PS de Carvalho, FE Leal, MA Soares - Frontiers in Oncology, 2021 - frontiersin.org
Non-Hodgkin lymphoma is the most common malignancy affecting people living with HIV
(PLWH). Among its several subtypes, diffuse large B-cell lymphoma (DLBCL) is an important …

Dysregulation of memory B cells and circulating T follicular helper cells is a predictor of poor immune recovery in HIV‐infected patients on antiretroviral therapy

Y Liu, Z Li, X Lu, YQ Kuang, D Kong… - Journal of Medical …, 2023 - Wiley Online Library
T follicular helper (Tfh) cells and their interactions with B cells within the germinal center play
extensive roles in human immunodeficiency virus (HIV) pathology. However, their …

Seroconversion and antibody persistence after yellow fever vaccination in people living with HIV: impact of baseline HIV viral load and yellow fever seropositivity

C Martin, E Florence, C Domingo… - Journal of travel …, 2022 - academic.oup.com
Background Data on seroconversion rates following yellow fever (YF) vaccine and effect of
revaccination in people living with HIV (PLWH) are scarce. We aimed at determining key …

Hierarchical Clustering and Trajectory Analyses Reveal Viremia-Independent B-Cell Perturbations in HIV-2 Infection

E Johansson, PF Kerkman, L Scharf, J Lindman… - Cells, 2022 - mdpi.com
Time to AIDS in HIV-2 infection is approximately twice as long compared to in HIV-1
infection. Despite reduced viremia, HIV-2-infected individuals display signs of chronic …

CD27− CD38+ B cells accumulated in early HIV infection exhibit transitional profile and promote HIV disease progression

Y Fu, Z Zhang, Z Yang, Y Jiang, X Han, J Xu, Z Chu… - Cell Reports, 2021 - cell.com
Although peripheral B cell dysfunction in early HIV infection is established, how B cell
subsets are altered by HIV infection is poorly understood. While investigating B cell subsets …