With the growing problem of the emergence of antibiotic-resistant bacteria, the search for alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …
RJ Lee, JM Kofonow, PL Rosen… - The Journal of …, 2014 - Am Soc Clin Investig
Bitter taste receptors (T2Rs) in the human airway detect harmful compounds, including secreted bacterial products. Here, using human primary sinonasal air-liquid interface …
R Bucki, K Leszczyńska, A Namiot… - Archivum immunologiae et …, 2010 - Springer
The antimicrobial peptide LL-37 is the only known member of the cathelicidin family of peptides expressed in humans. LL-37 is a multifunctional host defense molecule essential …
DL Hamilos - Journal of Allergy and Clinical Immunology, 2014 - Elsevier
There has been considerable investigation of host-microbial interactions in patients with chronic rhinosinusitis (CRS) in hopes of elucidating mechanisms of disease and better …
AM McDermott - Ophthalmic research, 2009 - karger.com
Antimicrobial peptides (AMPs) such as defensins and cathelicidins are small peptides with broad-spectrum activity against bacteria, fungi and viruses. In addition, several AMPs …
M Memariani, H Memariani - World Journal of Microbiology and …, 2024 - Springer
The threat of fungal diseases is substantially underestimated worldwide, but they have serious consequences for humans, animals, and plants. Given the limited number of existing …
EH Ooi, PJ Wormald, LW Tan - American journal of rhinology, 2008 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) is a common inflammatory disorder of the paranasal sinuses. An abnormal host response to common bacterial or fungal pathogens is …
EJ Cleland, A Bassioni, S Boase… - International forum of …, 2014 - Wiley Online Library
Background Our understanding of fungi in chronic rhinosinusitis (CRS) has been limited by previously employed detection techniques. This study examines the fungal component of the …