Arabidopsis telomerase takes off by uncoupling enzyme activity from telomere length maintenance in space

BB Barcenilla, AD Meyers, C Castillo-González… - Nature …, 2023 - nature.com
Spaceflight-induced changes in astronaut telomeres have garnered significant attention in
recent years. While plants represent an essential component of future long-duration space …

Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing

TM Al-Turki, DG Maranon, CB Nelson… - Communications …, 2024 - nature.com
Telomeres are repetitive nucleoprotein complexes at chromosomal termini essential for
maintaining genome stability. Telomeric RNA, or TERRA, is a previously presumed long …

Aging and putative frailty biomarkers are altered by spaceflight

A Camera, M Tabetah, V Castañeda, JK Kim… - Scientific Reports, 2024 - nature.com
Human space exploration poses inherent risks to astronauts' health, leading to molecular
changes that can significantly impact their well-being. These alterations encompass …