The biology of regeneration failure and success after spinal cord injury
Since no approved therapies to restore mobility and sensation following spinal cord injury
(SCI) currently exist, a better understanding of the cellular and molecular mechanisms …
(SCI) currently exist, a better understanding of the cellular and molecular mechanisms …
Oxidative stress and regeneration
Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …
function and is limited respecting complexity of specific organ structures and the level of …
Reactive astrogliosis: implications in spinal cord injury progression and therapy
X Li, M Li, L Tian, J Chen, R Liu… - Oxidative medicine and …, 2020 - Wiley Online Library
Astrocytes are the most populous glial cells in the central nervous system (CNS). They are
essential to CNS physiology and play important roles in the maintenance of homeostasis …
essential to CNS physiology and play important roles in the maintenance of homeostasis …
The role of astrocytes in neuroprotection after brain stroke: potential in cell therapy
A Becerra-Calixto, GP Cardona-Gómez - Frontiers in molecular …, 2017 - frontiersin.org
Astrocytes are commonly involved in negative responses through their hyperreactivity and
glial scar formation in excitotoxic and/or mechanical injuries. But, astrocytes are also …
glial scar formation in excitotoxic and/or mechanical injuries. But, astrocytes are also …
Neuron-astrocyte omnidirectional signaling in neurological health and disease
D Pathak, K Sriram - Frontiers in molecular neuroscience, 2023 - frontiersin.org
Astrocytes are an abundantly distributed population of glial cells in the central nervous
system (CNS) that perform myriad functions in the normal and injured/diseased brain …
system (CNS) that perform myriad functions in the normal and injured/diseased brain …
The contribution of gliosis to diffusion tensor anisotropy and tractography following traumatic brain injury: validation in the rat using Fourier analysis of stained tissue …
Diffusion tensor imaging is highly sensitive to the microstructural integrity of the brain and
has uncovered significant abnormalities following traumatic brain injury not appreciated …
has uncovered significant abnormalities following traumatic brain injury not appreciated …
The role of astrocytes in the neurorepair process
RA Chiareli, GA Carvalho, BL Marques… - Frontiers in cell and …, 2021 - frontiersin.org
Astrocytes are highly specialized glial cells responsible for trophic and metabolic support of
neurons. They are associated to ionic homeostasis, the regulation of cerebral blood flow and …
neurons. They are associated to ionic homeostasis, the regulation of cerebral blood flow and …
Mechanisms of endogenous neuroprotective effects of astrocytes in brain injury
MA Bylicky, GP Mueller, RM Day - Oxidative medicine and …, 2018 - Wiley Online Library
Astrocytes, once believed to serve only as “glue” for the structural support of neurons, have
been demonstrated to serve critical functions for the maintenance and protection of neurons …
been demonstrated to serve critical functions for the maintenance and protection of neurons …
Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy
Glaucoma is a complex neurodegenerative disorder that is expected to affect 80 million
people by the end of this decade. Retinal ganglion cells (RGCs) are the most affected cell …
people by the end of this decade. Retinal ganglion cells (RGCs) are the most affected cell …
Structural remodeling of astrocytes in the injured CNS
Astrocytes respond to all forms of CNS insult and disease by becoming reactive, a
nonspecific but highly characteristic response that involves various morphological and …
nonspecific but highly characteristic response that involves various morphological and …