Just passing through: Deploying aquaporins in microbial cell factories

LR Jenkins Sánchez, LM Sips… - Biotechnology …, 2024 - Wiley Online Library
As microbial membranes are naturally impermeable to even the smallest biomolecules,
transporter proteins are physiologically essential for normal cell functioning. This makes …

Intracellular Plasmodium aquaporin 2 is important for sporozoite production in the mosquito vector and malaria transmission

AJ Bailey, CV Ukegbu, M Giorgalli… - Proceedings of the …, 2023 - National Acad Sciences
Malaria remains a devastating disease and, with current measures failing to control its
transmission, there is a need for novel interventions. A family of proteins that have long been …

Current Trends in Nanotechnology-based Drug Delivery Systems for the Diagnosis and Treatment of Malaria: A Review

R Deshmukh, B Dewangan, RK Harwansh… - Current Drug …, 2024 - ingentaconnect.com
Malaria is still a major endemic disease transmitted in humans via Plasmodium-infected
mosquitoes. The eradication of malarial parasites and the control measures have been …

[HTML][HTML] Isoliquiritigenin from licorice root: A multi-stage anti-malarial with synergistic impact on multidrug-resistant P. falciparum

S Kumar, PR Mina, D Bhatt, P Kumar, M Singh… - Pharmacological …, 2024 - Elsevier
Introduction Malaria control is hindered by drug-resistant parasites, leading to a shortage of
effective drugs. There is a need to find new, better antimalarial drug. Traditional Chinese …

Evaluation of Au(III) complexes as Plasmodium falciparum aquaglyceroporin (PfAQP) inhibitors by in silico and in vitro methods

F Balgera, MK Tijani, J Wennerberg… - JBIC Journal of …, 2024 - Springer
The onset of resistance to artemisinin for malaria treatment has stimulated the quest for
novel antimalarial drugs. Herein, the gold (III) coordination complexes Aubipy [Au (bipy) …

Intracellular Plasmodium aquaporin 2 is required for sporozoite production in the mosquito vector and malaria transmission

AJ Bailey, CV Ukegbu, M Giorgalli, TRB Besson… - bioRxiv, 2023 - biorxiv.org
Malaria remains a devastating disease and, with current measures failing to control its
transmission, there is a need for novel interventions. A family of proteins that have long been …