Endothelin: 30 years from discovery to therapy

M Barton, M Yanagisawa - Hypertension, 2019 - Am Heart Assoc
Discovered in 1987 as a potent endothelial cell–derived vasoconstrictor peptide, endothelin-
1 (ET-1), the predominant member of the endothelin peptide family, is now recognized as a …

Vascular signaling in allogenic solid organ transplantation–the role of endothelial cells

L Kummer, M Zaradzki, V Vijayan, R Arif… - Frontiers in …, 2020 - frontiersin.org
Graft rejection remains the major obstacle after vascularized solid organ transplantation.
Endothelial cells, which form the interface between the transplanted graft and the host's …

The role of endothelin II type A receptor (ETAR) in transplant injury

K Nowańska, K Wiśnicki, M Kuriata-Kordek… - Transplant …, 2022 - Elsevier
Purpose of review Antibody-mediated rejection is the leading cause of deterioration of graft
function and graft loss after kidney transplantation. Recent studies have reported an …

Plasma endothelin-1 and risk of death and hospitalization in patients undergoing maintenance hemodialysis

P Li, IM Schmidt, V Sabbisetti, MC Tio… - Clinical Journal of the …, 2020 - journals.lww.com
Results The median plasma endothelin-1 level was 2.02 (interquartile range, 1.57–2.71)
pg/ml. During a median follow-up period of 28 (interquartile range, 21–29) months, 253 …

Serum biomarkers of cardiovascular remodelling reflect extra-valvular cardiac damage in patients with severe aortic stenosis

L Bäz, G Dannberg, K Grün, J Westphal… - International journal of …, 2020 - mdpi.com
In patients with aortic stenosis (AS), a novel staging classification of extra-valvular left and
right heart damage with prognostic relevance was introduced in 2017. The aim of the study …

Noninvasive methods to reduce cardiac complications postheart transplant

L Zhou, A Wolfson, AS Vaidya - Current Opinion in Organ …, 2022 - journals.lww.com
Noninvasive imaging and biomarker testing continue to show promise as alternatives to
invasive testing for allograft rejection. Continued validation of their effectiveness may lead to …

The biological parallels between atherosclerosis and cardiac allograft vasculopathy: implications for solid organ chronic rejection.

AA Otunla, K Shanmugarajah, AH Davies… - Cardiology in …, 2022 - journals.lww.com
Atherosclerosis and solid organ chronic rejection are pervasive chronic disease states that
account for significant morbidity and mortality in developed countries. Recently, a series of …

[PDF][PDF] 再次心脏移植的研究进展

柴军武, 王凯, 孔祥荣 - 实用器官移植电子杂志, 2019 - zqenorth.com.cn
·综述· 再次心脏移植的研究进展 Page 1 ·152· 《实用器官移植电子杂志》 2019 年3 月第7 卷第2
期 Prac J Organ Transplant(Electronic Version), March 2019,Vol.7,No.2 ·综述· 再次心脏移植 …

Role protilátek proti HLA a non HLA antigenům pro transplantace orgánů.

E Svobodová - 2023 - dspace.cuni.cz
Rejekce je významnou komplikací po transplantaci a také za jeden z hlavních důvodů ztráty
funkce štěpu. Je vyvolána odpovědí imunitního systému příjemce orgánu na základě setkání …

Изменение активности альфа-2-макроглобулина и содержания эндотелина в слезной жидкости при моделировании атрофии ретинального пигментного …

НВ Нероева, НБ Чеснокова, ЛА Катаргина… - Российский …, 2022 - roj.igb.ru
Аннотация Цель работы—оценить возможность использования определения уровня
альфа-2-макроглобулина (2-МГ) и эндотелина-1 (ЭТ-1) в слезной жидкости (СЖ) для …