[HTML][HTML] A systematic review on the bidirectional relationship between trauma-related psychopathology and reproductive aging

AR Arnold, T Prochaska, M Fickenwirth… - Journal of Mood & …, 2024 - Elsevier
Objective Natural variation in ovarian steroid hormones across the female lifespan
contributes to an increased risk for depressive and posttraumatic stress disorder (PTSD) …

Longitudinal hair cortisol in bipolar disorder and a mechanism based on HPA dynamics

T Milo, L Maimon, B Cohen, D Haran, D Segman… - Iscience, 2024 - cell.com
Bipolar disorder (BD) is marked by fluctuating mood states over months to years, often with
elevated cortisol levels. Elevated cortisol can also trigger mood episodes. Here, we combine …

Oscillations in delayed positive feedback systems

CJ Ryzowicz, R Bertram, B Karamched - Physical Chemistry Chemical …, 2024 - pubs.rsc.org
Positive feedback loops exist in many biological circuits important for organismal function. In
this work, we investigate how temporal delay affects the dynamics of two canonical positive …

Hormone circuit analysis explains why most HPA drugs fail for mood disorders and predicts the few that work

T Milo, S Nir Halber, M Raz, A Mayo, U Alon - bioRxiv, 2024 - biorxiv.org
Elevated cortisol causes morbidity in chronic stress and mood disorders, including metabolic
and cardiovascular diseases. There is therefore interest in developing drugs that lower …