Nutrition and metabolic adaptations in physiological and complicated pregnancy: focus on obesity and gestational diabetes

S Parrettini, A Caroli, E Torlone - Frontiers in endocrinology, 2020 - frontiersin.org
Pregnancy offers a window of opportunity to program the future health of both mothers and
offspring. During gestation, women experience a series of physical and metabolic …

Relationship between maternal vitamin D levels and adverse outcomes

H Zhang, S Wang, L Tuo, Q Zhai, J Cui, D Chen, D Xu - Nutrients, 2022 - mdpi.com
Vitamin D (VD), a fat-soluble vitamin, has a variety of functions that are important for growth
and development, including regulation of cell differentiation and apoptosis, immune system …

Therapeutic strategies targeting folate receptor α for ovarian cancer

J Mai, L Wu, L Yang, T Sun, X Liu, R Yin… - Frontiers in …, 2023 - frontiersin.org
Epithelial ovarian cancer (EOC) is the deadliest gynecological cancer, and presents a major
clinical challenge due to limited treatment options. Folate receptor alpha (FRα), encoded by …

Altered expression of nutrient transporters in syncytiotrophoblast membranes in preeclampsia placentae

N Joshi, A Sahay, A Mane, D Sundrani, K Randhir… - Placenta, 2023 - Elsevier
Introduction Expression of nutrient transporters in the placenta affects fetal growth. This
study reports the protein expression of nutrient transporters in the syncytial membranes …

Influence of maternal one carbon metabolites on placental programming and long term health

J Nema, N Joshi, D Sundrani, S Joshi - Placenta, 2022 - Elsevier
Studies have shown that the maternal nutrition during critical periods of development not
only influences fetal growth but also plays a significant role in determining the risk of chronic …

The immediate and long-term metabolic implications of maternal obesity and gestational weight gain

S Mondal, A Saha, SC Biswas, S Mukhopadhyay - Metabolic Syndrome, 2024 - Elsevier
Pre-pregnancy overweight/obesity and excess gestational weight gain (GWG) can not only
affect perinatal outcomes but also adversely impact long-term materno-fetal cardiometabolic …

[PDF][PDF] 胎盘叶酸转运体与妊娠并发症的关系研究进展

唐红波, 丁新, 秦春雨, 刘祺, 韩朝宏… - 中国药学 …, 2020 - journal11.magtechjournal.com
妊娠期母体向胎儿输送营养物质只能通过胎盘, 叶酸在胎盘发育和胎儿生长中起着重要的作用,
参与细胞分裂, 胚胎发生和胎儿生长. 胎盘叶酸转运能力是胎儿应用叶酸的限制步骤之一, 因而 …

叶酸载体基因多态性与胎儿神经管缺陷.

裴娇娇, 谢江燕, 伍小莉 - Journal of International …, 2021 - search.ebscohost.com
叶酸是一组水溶性维生素(维生素B9) 的天然存在形式, 作为体内一碳单位转移酶系的辅酶,
为体内甲基化反应和核酸合成提供重要原材料, 其衍生物也是许多一碳单位转移反应的底物 …

Drug transport in the placenta

Q Mao, V Ganapathy… - … characterization and role …, 2022 - Wiley Online Library
Summary Statistics indicate that 64% of pregnant women in the United States ingest at least
one licit drug other than a vitamin or mineral supplement during pregnancy for the treatment …

Prenatal diagnosis of neural tube defects

A Milunsky - JAMA, 1977 - jamanetwork.com
To the Editor.—I was surprised to read in the report by Macri et al (236: 1251, 1976) that they
were aware of no prospectively prenatally diagnosed cases of open neural tube defects …